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UniProt ID Gene Symbol Protein Name Organism Length Action
H3BU31 RPL4 Ribosomal protein L4 Homo sapiens (Human) 171 aa

Protein Details: H3BU31 (RPL4)

Protein Information
AccessionH3BU31
Protein NamesRibosomal protein L4
Gene SymbolRPL4
OrganismHomo sapiens (Human)
Length171 aa
IsoformsNo isoforms
Related PMIDs 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MACARPLISV11YSEKGESSGK21NVTLPAVFKA31PIRPDIVNFV41HTNLRKNNRQ
51-10051PYAVSELAGH61QTSAESWGTG71RAVARIPRVR81GGGTHRSGQG91AFGNMCRGGR
101-150101MFAPTKTWRR111WHRRKNPLKN121LRIMLKLNPY131AKTMRRNTIL141RQARNHKLRV
151-171151DKAAAAAAAL161QAKSDEKAAV171A
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
3 SWISSPALM DBPTM CYSMODDB Large ribosomal subunit protein uL4 domain superfamily
HeLa (29575903)
cerebral cortex (36430497)
GPS-Palm: 0.97
Deep-Palm: 0.04
96 - -
LNCaP (31251020)
GPS-Palm: 0.87
Deep-Palm: 0.79
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
LNCaP
Specificity: 0.400
4/4 (100.0%)
3
PC3
Specificity: 0.300
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Cerebral Cortex (Mass)
Specificity: 0.200
2/4 (50.0%)
1
LNCaP cells (Mass)
Specificity: 0.100
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
97 R → C 0.002506 SNP Missense Mutation COAD
143 R → C 0.002141 SNP Missense Mutation SKCM
200 R → C 0.001887 SNP Missense Mutation UCEC
268 R → C 0.001887 SNP Missense Mutation UCEC
336 R → C 0.002033 SNP Missense Mutation THCA
342 R → C 0.001764 SNP Missense Mutation LUAD