Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H3BU78 ALDOA Fructose-bisphosphate aldolase (EC 4.1.2.13) Homo sapiens (Human) 204 aa

Protein Details: H3BU78 (ALDOA)

Protein Information
AccessionH3BU78
Protein NamesFructose-bisphosphate aldolase (EC 4.1.2.13)
Gene SymbolALDOA
OrganismHomo sapiens (Human)
Length204 aa
IsoformsNo isoforms
Related PMIDs 31251020 32944167 36430497
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501RRFYRQLLLT11ADDRVNPCIG21GVILFHETLY31QKADDGRPFP41QVIKSKGGVV
51-10051GIKVDKGVVP61LAGTNGETTT71QGLDGLSERC81AQYKKDGADF91AKWRCVLKIG
101-150101EHTPSALAIM111ENANVLARYA121SICQQVLAAV131YKALSDHHIY141LEGTLLKPNM
151-200151VTPGHACTQK161FSHEEIAMAT171VTALRRTVPP181AVTGITFLSG191GQSEEEASIN
201-204201LNAI
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
18 SWISSPALM DBPTM CYSMODDB Aldolase Aldolase-type TIM barrel Fructose-bisphosphate aldolase class-I Fructose-bisphosphate aldolase, class-I
HeLa (29575903)
-
GPS-Palm: 0.80
Deep-Palm: 0.81
80 - - -
GPS-Palm: 0.77
Deep-Palm: 0.91
95 - - -
Deep-Palm: 0.90
123 - - -
GPS-Palm: 0.91
Deep-Palm: 0.94
157 - - -
Deep-Palm: 0.62
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
PC3
Specificity: 0.400
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
2
LNCaP
Specificity: 0.200
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
76 G → C 0.002506 SNP Missense Mutation COAD
149 R → C 0.002506 SNP Missense Mutation COAD
201 R → C 0.002545 SNP Missense Mutation GBM
201 R → C 0.003774 SNP Missense Mutation UCEC
204 Y → C 0.001887 SNP Missense Mutation UCEC