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UniProt ID Gene Symbol Protein Name Organism Length Action
H3BV67 DOK4 Docking protein 4 Homo sapiens (Human) 246 aa

Protein Details: H3BV67 (DOK4)

Protein Information
AccessionH3BV67
Protein NamesDocking protein 4
Gene SymbolDOK4
OrganismHomo sapiens (Human)
Length246 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MATNFSDIVK11QGYVKMKSRK21LGIYRRCWLV31FRKSSSKGPQ41RLEKYPDEKS
51-10051VCLRGCPKVT61EISNVKCVTR71LPKETKRQAV81AIIFTDDSAR91TFTCDSELEA
101-150101EEWYKTLSVE111CLGSRLNDIS121LGEPDLLAPG131VQCEQTDRFN141VFLLPCPNLD
151-200151VYGECKLQIT161HENIYLWDIH171NPRVKLVSWP181LCSLRRYGRD191ATRFTFEAGR
201-246201MCDAGEGLYT211FQTQEGEQIY221QRVHSATLAI231AEQHKRVLLE241MEKNVR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
27 PH domain-like PH-like domain superfamily - -
GPS-Palm: 0.86
Deep-Palm: 0.92
52 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.92
Deep-Palm: 0.93
56 - - -
GPS-Palm: 0.78
Deep-Palm: 0.95
67 - - -
GPS-Palm: 0.90
Deep-Palm: 0.91
94 - - -
Deep-Palm: 0.40
111 - - -
GPS-Palm: 0.81
Deep-Palm: 0.97
133 - - -
Deep-Palm: 0.90
146 - - -
Deep-Palm: 0.48
155 - - -
Deep-Palm: 0.10
182 - - -
GPS-Palm: 0.96
Deep-Palm: 0.59
202 - - -
GPS-Palm: 0.78
Deep-Palm: 0.76
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
173 R → C 0.001887 SNP Missense Mutation UCEC
185 R → C 0.001887 SNP Missense Mutation UCEC
187 Y → C 0.002427 SNP Missense Mutation BLCA
193 R → C 0.002506 SNP Missense Mutation COAD
202 C → C 0.001887 SNP Silent UCEC
271 W → Cfs*39 0.002294 DEL Frame Shift Del OV
52* C → ? 0.001969 SNP Nonsense Mutation HNSC