Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7BZT7 | ESD | S-formylglutathione hydrolase (EC 3.1.2.12) | Homo sapiens (Human) | 230 aa |
Protein Details: H7BZT7 (ESD)
Protein Information
| Accession | H7BZT7 |
|---|---|
| Protein Names | S-formylglutathione hydrolase (EC 3.1.2.12) |
| Gene Symbol | ESD |
| Organism | Homo sapiens (Human) |
| Length | 230 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XLTCTEQNFI11SKSGYHQSAS21EHGLVVIAPD31TSPRGCNIKG41EDESWDFGTG
51-10051AGFYVDATED61PWKTNYRMYS71YVTEELPQLI81NANFPVDPQR91MSIFGHSMGG
101-150101HGALICALKN111PGKYKSVSAF121APICNPVLCP131WGKKAFSGYL141GTDQSKWKAY
151-200151DATHLVKSYP161GSQLDILIDQ171GKDDQFLLDG181QLLPDNFIAA191CTEKKIPVVF
201-230201RLQEHGRVKS211GLHSLKRISL221RFVVIESTTE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 4 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.03
|
|
| 36 | Alpha/Beta hydrolase fold Esterase-like S-formylglutathione hydrolase | - | - |
Deep-Palm: 0.90
|
|
| 106 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.70
|
|
| 124 | SWISSPALM DBPTM CYSMODDB | Putative esterase | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.87
Deep-Palm: 0.76
|
| 129 | SWISSPALM DBPTM CYSMODDB | Putative esterase | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.88
Deep-Palm: 0.82
|
| 191 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.85
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.444
4/4 (100.0%)
1
frontal cortex
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.444
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 92 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 183 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |