Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7C131 | ACAA1 | acetyl-CoA C-acetyltransferase (EC 2.3.1.9) | Homo sapiens (Human) | 290 aa |
Protein Details: H7C131 (ACAA1)
Protein Information
| Accession | H7C131 |
|---|---|
| Protein Names | acetyl-CoA C-acetyltransferase (EC 2.3.1.9) |
| Gene Symbol | ACAA1 |
| Organism | Homo sapiens (Human) |
| Length | 290 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 32651440 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.822
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
37
LNCaP cells
Specificity: 0.822
37/46 (80.4%)
3
PC3 cells
Specificity: 0.067
3/4 (75.0%)
3
Cerebral cortex
Specificity: 0.067
3/4 (75.0%)
1
Jurkat T cells
Specificity: 0.022
1/25 (4.0%)
1
U937 cells
Specificity: 0.022
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MRPEQLGDIC11VGNVLQPGAG21AIMARIAQFL31SDIPETVPLS41TVNRQCSSGL
51-10051QAVASIAGGI61RNGSYDIGMA71CGITSENVAE81RFGISREKQD91TFALASQQKA
101-150101ARAQSKGCFQ111AEIVPVTTTV121HDDKGTKRSI131TVTQDEGIRP141STTMEGLAKL
151-200151KPAFKKDGST161TAGNSSQVSD171GAAAILLARR181SKAEELGLPI191LGVLRSYAVV
201-250201GVPPDIMGIG211PAYAIPVALQ221KAGLTVSDVD231IFEINEAFAS241QAAYCVEKLR
251-290251LPPEKVNPLG261GAVALGHPLG271CTGARQVITL281LNELKRRGKR
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 10 | Prediction (Low) | - | - |
| 46 | Prediction (Low) | - | - |
| 71 | Prediction (Low) | - | - |
| 108 | Prediction (Medium) | - | - |
| 245 | Prediction (Low) | - | - |
| 271 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 123 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 396 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |