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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H7C192 ARL6IP6 ADP ribosylation factor like GTPase … Homo sapiens (Human) 219 aa

Protein Details: H7C192 (ARL6IP6)

Protein Information
AccessionH7C192
Protein NamesADP ribosylation factor like GTPase 6 interacting protein 6 (ADP-ribosylation-like factor 6 interacting protein 6, isoform CRA_a)
Gene SymbolARL6IP6
OrganismHomo sapiens (Human)
Length219 aa
IsoformsNo isoforms
Related PMIDs 19137006 32944167
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSFAESGWRS11ALRRRGPGTP21GPVARPSYSS31FTQGDSWGEG41EVDEEEGCDQ
51-10051VARDLRAEFS61AGAWSEPRKR71SVLPPDGNGS81PVLPDKRNGI91FPAAAGSRAQ
101-150101PRRWPVQVLS111ILCSLLFAIL121LAFLLAIAYL131IVKELHAENL141KNEDDVDTGL
151-200151LGFWTLLIIS161LTAGFSCCSF171SWTVTYFDSF181EPGMFPPTPL191SPARFNSSTP
201-219201RIYPREISAD211SHHPPKTCS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
48 - - -
Deep-Palm: 0.95
113 - - -
Deep-Palm: 0.96
167 - - -
GPS-Palm: 0.67
Deep-Palm: 0.16
168 - - -
Deep-Palm: 0.19
218 - - -
GPS-Palm: 0.92
Deep-Palm: 0.01
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
2
Jurkat T cell
Specificity: 0.500
2/2 (100.0%)
2
PC3
Specificity: 0.500
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
48 C → Afs*83 0.001969 DEL Frame Shift Del HNSC
89 G → C 0.001887 SNP Missense Mutation UCEC
169 S → C 0.001969 SNP Missense Mutation HNSC
172 W → C 0.001014 SNP Missense Mutation BRCA