Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7C1J3 | DHTKD1 | 2-oxoadipate dehydrogenase complex component E1 … | Homo sapiens (Human) | 160 aa |
Protein Details: H7C1J3 (DHTKD1)
Protein Information
| Accession | H7C1J3 |
|---|---|
| Protein Names | 2-oxoadipate dehydrogenase complex component E1 (2-oxoadipate dehydrogenase, mitochondrial) (Alpha-ketoadipate dehydrogenase) (Dehydrogenase E1 and transketolase domain-containing protein 1) (Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial) |
| Gene Symbol | DHTKD1 |
| Organism | Homo sapiens (Human) |
| Length | 160 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501GRQQSRQDGD11YSPDNSAQPG21DRVICLQVHG31DASFCGQGIV41PETFTLSNLP
51-10051HFRIGGSVHL61IVNNQLGYTT71PAERGRSSLY81CSDIGKLVGC91AIIHVNGDSP
101-150101EEVVRATRLA111FEYQRQFRKD121VIIDLLCYRQ131WGHNELDEPF141YTNPIMYKII
151-160151RYNYKPLCDM
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 25 | - | - | - |
Deep-Palm: 0.47
|
|
| 35 | 2-oxoglutarate dehydrogenase E1 component | - | - |
Deep-Palm: 0.63
|
|
| 81 | - | - | - |
Deep-Palm: 0.89
|
|
| 90 | - | - | - |
Deep-Palm: 0.90
|
|
| 127 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.82
|
|
| 158 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 173 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 302 | R → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 391 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 417 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 417 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 448 | M → Cfs*25 | 0.001887 | DEL | Frame Shift Del | UCEC |
| 485 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 558 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 679 | F → C | 0.002020 | SNP | Missense Mutation | PRAD |