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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H7C1J3 DHTKD1 2-oxoadipate dehydrogenase complex component E1 … Homo sapiens (Human) 160 aa

Protein Details: H7C1J3 (DHTKD1)

Protein Information
Accession H7C1J3
Protein Names 2-oxoadipate dehydrogenase complex component E1 (2-oxoadipate dehydrogenase, mitochondrial) (Alpha-ketoadipate dehydrogenase) (Dehydrogenase E1 and transketolase domain-containing protein 1) (Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial)
Gene Symbol DHTKD1
Organism Homo sapiens (Human)
Length 160 aa
Isoforms No isoforms
Related PMIDs 31251020
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
20
LNCaP cells
Specificity: 1.000
20/46 (43.5%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501GRQQSRQDGD11YSPDNSAQPG21DRVICLQVHG31DASFCGQGIV41PETFTLSNLP
51-10051HFRIGGSVHL61IVNNQLGYTT71PAERGRSSLY81CSDIGKLVGC91AIIHVNGDSP
101-150101EEVVRATRLA111FEYQRQFRKD121VIIDLLCYRQ131WGHNELDEPF141YTNPIMYKII
151-160151RYNYKPLCDM
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
127 Prediction (High) - -
158 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
173 S → C 0.001969 SNP Missense Mutation HNSC
302 R → C 0.002747 SNP Missense Mutation LIHC
391 G → C 0.001764 SNP Missense Mutation LUAD
417 R → C 0.001014 SNP Missense Mutation BRCA
417 R → C 0.001887 SNP Missense Mutation UCEC
448 M → Cfs*25 0.001887 DEL Frame Shift Del UCEC
485 Y → C 0.002288 SNP Missense Mutation STAD
558 S → C 0.002033 SNP Missense Mutation LUSC
679 F → C 0.002020 SNP Missense Mutation PRAD