Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H7C1S2 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Homo sapiens (Human) 231 aa

Protein Details: H7C1S2 (ATIC)

Protein Information
Accession H7C1S2
Protein Names 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Gene Symbol ATIC
Organism Homo sapiens (Human)
Length 231 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.913
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
21
LNCaP cells
Specificity: 0.913
21/46 (45.7%)
2
PC3 cells
Specificity: 0.087
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501XIFLQVSDGI11IAPGYEEEAL21TILSKKKNGN31YCVLQMDQSY41KPDENEVRTL
51-10051FGLHLSQKRN61NGVVDKSLFS71NVVTKNKDLP81ESALRDLIVA91TIAVKYTQSN
101-150101SVCYAKNGQV111IGIGAGQQSR121IHCTRLAGDK131ANYWWLRHHP141QVLSMKFKTG
151-200151VKRAEISNAI161DQYVTGTIGE171DEDLIKWKAL181FEEVPELLTE191AEKKEWVEKL
201-231201TEVSISSDAF211FPFRDNVDRA221KRVSMELGAF231A
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
32 Prediction (Medium) - -
103 Prediction (Low) - -
123 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
197 Y → C 0.002033 SNP Missense Mutation LUSC
241 C → C 0.002288 SNP Silent STAD
241 C → C 0.001887 SNP Silent UCEC
564 G → C 0.001969 SNP Missense Mutation HNSC
575 C → C 0.003460 SNP Silent CESC