Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7C341 | SF3B1 | Splicing factor 3b subunit 1 | Homo sapiens (Human) | 241 aa |
Protein Details: H7C341 (SF3B1)
Protein Information
| Accession | H7C341 |
|---|---|
| Protein Names | Splicing factor 3b subunit 1 |
| Gene Symbol | SF3B1 |
| Organism | Homo sapiens (Human) |
| Length | 241 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.921
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.921
35/46 (76.1%)
3
PC3 cells
Specificity: 0.079
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501XSKYALHCRE11TGDLFVLQLK21GMHKMTPPIK31DLLPRLTPIL41KNRHEKVQEN
51-10051CIDLVGRIAD61RGAEYVSARE71WMRICFELLE81LLKAHKKAIR91RATVNTFGYI
101-150101AKAIGPHDVL111ATLLNNLKVQ121ERQNRVCTTV131AIAIVAETCS141PFTVLPALMN
151-200151EYRVPELNVQ161NGVLKSLSFL171FEYIGEMGKD181YIYAVTPLLE191DALMDRDLVH
201-241201RQTASAVVQH211MSLGVYGFGC221EDSLNHLLNY231VWPNVFETSP241H
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 8 | Prediction (Medium) | - | - |
| 51 | Prediction (Low) | - | - |
| 75 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 127 | Prediction (Medium) | - | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 101 | Y → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 286 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 397 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 397 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 524 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 549 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 588 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 625 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 625 | R → C | 0.004283 | SNP | Missense Mutation | SKCM |
| 625 | R → C | 0.075000 | SNP | Missense Mutation | UVM |
| 765 | Y → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 765 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 965 | C → S | 0.002033 | SNP | Missense Mutation | LUSC |
| 1035 | C → G | 0.001887 | SNP | Missense Mutation | UCEC |
| 1059 | C → R | 0.001014 | SNP | Missense Mutation | BRCA |
| 1297 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 1297 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |