Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7C341 | SF3B1 | Splicing factor 3b subunit 1 | Homo sapiens (Human) | 241 aa |
Protein Details: H7C341 (SF3B1)
Protein Information
| Accession | H7C341 |
|---|---|
| Protein Names | Splicing factor 3b subunit 1 |
| Gene Symbol | SF3B1 |
| Organism | Homo sapiens (Human) |
| Length | 241 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XSKYALHCRE11TGDLFVLQLK21GMHKMTPPIK31DLLPRLTPIL41KNRHEKVQEN
51-10051CIDLVGRIAD61RGAEYVSARE71WMRICFELLE81LLKAHKKAIR91RATVNTFGYI
101-150101AKAIGPHDVL111ATLLNNLKVQ121ERQNRVCTTV131AIAIVAETCS141PFTVLPALMN
151-200151EYRVPELNVQ161NGVLKSLSFL171FEYIGEMGKD181YIYAVTPLLE191DALMDRDLVH
201-241201RQTASAVVQH211MSLGVYGFGC221EDSLNHLLNY231VWPNVFETSP241H
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.03
|
|
| 51 | Armadillo-type fold Splicing factor 3B subunit 1-like | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.91
|
|
| 75 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.97
|
| 127 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.73
|
|
| 139 | - | - | - |
Deep-Palm: 0.76
|
|
| 220 | - | - | - |
Deep-Palm: 0.15
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
LNCaP
Specificity: 0.500
3/3 (100.0%)
3
PC3
Specificity: 0.500
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 101 | Y → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 286 | S → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 397 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 397 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 524 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 549 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 588 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 625 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 625 | R → C | 0.004283 | SNP | Missense Mutation | SKCM |
| 625 | R → C | 0.075000 | SNP | Missense Mutation | UVM |
| 765 | Y → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 765 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 965 | C → S | 0.002033 | SNP | Missense Mutation | LUSC |
| 1035 | C → G | 0.001887 | SNP | Missense Mutation | UCEC |
| 1059 | C → R | 0.001014 | SNP | Missense Mutation | BRCA |
| 1297 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 1297 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |