Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7C3C4 | SLC4A7 | Anion exchange protein | Homo sapiens (Human) | 801 aa |
Protein Details: H7C3C4 (SLC4A7)
Protein Information
| Accession | H7C3C4 |
|---|---|
| Protein Names | Anion exchange protein |
| Gene Symbol | SLC4A7 |
| Organism | Homo sapiens (Human) |
| Length | 801 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.848
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
28
LNCaP cells
Specificity: 0.848
28/46 (60.9%)
4
PC3 cells
Specificity: 0.121
4/4 (100.0%)
1
U937 cells
Specificity: 0.030
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501VMEVVEAEKI11VLLTSARFLF21LLLGPAGKAP31QYHEIGRSIA41TLMTDEIFHD
51-10051VAYKAKDRND61LLSGIDEFLD71QVTVLPPGEW81DPSIRIEPPK91SVPSQEKRKI
101-150101PVFHNGSTPT111LGETPKEAAH121HAGPELQRTG131RLFGGLILDI141KRKAPFFLSD
151-200151FKDALSLQCL161ASILFLYCAC171MSPVITFGGL181LGEATEGRIS191AIESLFGASL
201-250201TGIAYSLFAG211QPLTILGSTG221PVLVFEKILY231KFCRDYQLSY241LSLRTSIGLW
251-300251TSFLCIVLVA261TDASSLVCYI271TRFTEEAFAA281LICIIFIYEA291LEKLFDLGET
301-350301YAFNMHNNLD311KLTSYSCVCT321EPPNPSNETL331AQWKKDNITA341HNISWRNLTV
351-400351SECKKLRGVF361LGSACGHHGP371YIPDVLFWCV381ILFFTTFFLS391SFLKQFKTKR
401-450401YFPTKVRSTI411SDFAVFLTIV421IMVTIDYLVG431VPSPKLHVPE441KFEPTHPERG
451-500451WIISPLGDNP461WWTLLIAAIP471ALLCTILIFM481DQQITAVIIN491RKEHKLKKGA
501-550501GYHLDLLMVG511VMLGVCSVMG521LPWFVAATVL531SISHVNSLKV541ESECSAPGEQ
551-600551PKFLGIREQR561VTGLMIFILM571GLSVFMTSVL581KFIPMPVLYG591VFLYMGVSSL
601-650601KGIQLFDRIK611LFGMPAKHQP621DLIYLRYVPL631WKVHIFTVIQ641LTCLVLLWVI
651-700651KVSAAAVVFP661MMVLALVFVR671KLMDLCFTKR681ELSWLDDLMP691ESKKKKEDDK
701-750701KKKEKEEAER711MLQDDDDTVH721LPFEGGSLLQ731IPVKALKYSV741DPSIVNISDE
751-800751MAKTAQWKAL761SMNTENAKVT771RSNMSPDKPV781SVKISFEDEP791RKKYVDAETS
801-801801L
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 168 | Prediction (Low) | - | - |
| 233 | Prediction (Low) | - | - |
| 268 | Prediction (Low) | - | - |
| 283 | Prediction (Low) | - | - |
| 353 | Prediction (Medium) | - | - |
| 516 | Prediction (Low) | - | - |
| 676 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 86 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 129 | W → C | 0.002288 | SNP | Missense Mutation | STAD |
| 158 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 587 | L → _D588insCS*S | 0.001887 | INS | Nonsense Mutation | UCEC |
| 674 | F → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 806 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 806 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 820 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1119 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 965* | C → ? | 0.002288 | SNP | Nonsense Mutation | STAD |
| ? | ? → ? | 0.002033 | SNP | Missense Mutation | LUSC |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |