Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7C3C4 | SLC4A7 | Anion exchange protein | Homo sapiens (Human) | 801 aa |
Protein Details: H7C3C4 (SLC4A7)
Protein Information
| Accession | H7C3C4 |
|---|---|
| Protein Names | Anion exchange protein |
| Gene Symbol | SLC4A7 |
| Organism | Homo sapiens (Human) |
| Length | 801 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501VMEVVEAEKI11VLLTSARFLF21LLLGPAGKAP31QYHEIGRSIA41TLMTDEIFHD
51-10051VAYKAKDRND61LLSGIDEFLD71QVTVLPPGEW81DPSIRIEPPK91SVPSQEKRKI
101-150101PVFHNGSTPT111LGETPKEAAH121HAGPELQRTG131RLFGGLILDI141KRKAPFFLSD
151-200151FKDALSLQCL161ASILFLYCAC171MSPVITFGGL181LGEATEGRIS191AIESLFGASL
201-250201TGIAYSLFAG211QPLTILGSTG221PVLVFEKILY231KFCRDYQLSY241LSLRTSIGLW
251-300251TSFLCIVLVA261TDASSLVCYI271TRFTEEAFAA281LICIIFIYEA291LEKLFDLGET
301-350301YAFNMHNNLD311KLTSYSCVCT321EPPNPSNETL331AQWKKDNITA341HNISWRNLTV
351-400351SECKKLRGVF361LGSACGHHGP371YIPDVLFWCV381ILFFTTFFLS391SFLKQFKTKR
401-450401YFPTKVRSTI411SDFAVFLTIV421IMVTIDYLVG431VPSPKLHVPE441KFEPTHPERG
451-500451WIISPLGDNP461WWTLLIAAIP471ALLCTILIFM481DQQITAVIIN491RKEHKLKKGA
501-550501GYHLDLLMVG511VMLGVCSVMG521LPWFVAATVL531SISHVNSLKV541ESECSAPGEQ
551-600551PKFLGIREQR561VTGLMIFILM571GLSVFMTSVL581KFIPMPVLYG591VFLYMGVSSL
601-650601KGIQLFDRIK611LFGMPAKHQP621DLIYLRYVPL631WKVHIFTVIQ641LTCLVLLWVI
651-700651KVSAAAVVFP661MMVLALVFVR671KLMDLCFTKR681ELSWLDDLMP691ESKKKKEDDK
701-750701KKKEKEEAER711MLQDDDDTVH721LPFEGGSLLQ731IPVKALKYSV741DPSIVNISDE
751-800751MAKTAQWKAL761SMNTENAKVT771RSNMSPDKPV781SVKISFEDEP791RKKYVDAETS
801-801801L
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 159 | - | - | - |
Deep-Palm: 0.78
|
|
| 168 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.81
|
|
| 170 | - | - | - |
Deep-Palm: 0.83
|
|
| 233 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.90
|
|
| 255 | - | - | - |
Deep-Palm: 0.78
|
|
| 268 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.93
|
|
| 283 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.68
|
|
| 317 | - | - | - |
Deep-Palm: 0.10
|
|
| 319 | - | - | - |
Deep-Palm: 0.07
|
|
| 353 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.86
|
|
| 365 | - | - | - |
Deep-Palm: 0.87
|
|
| 379 | - | - | - |
Deep-Palm: 0.08
|
|
| 474 | - | - | - |
Deep-Palm: 0.63
|
|
| 516 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.65
|
|
| 544 | - | - |
LNCaP
(31251020)
|
Deep-Palm: 0.90
|
|
| 643 | - | - | - |
Deep-Palm: 0.75
|
|
| 676 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.89
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
PC3
Specificity: 0.444
4/4 (100.0%)
3
LNCaP
Specificity: 0.333
3/3 (100.0%)
1
U937 cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.111
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 86 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 129 | W → C | 0.002288 | SNP | Missense Mutation | STAD |
| 158 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 587 | L → _D588insCS*S | 0.001887 | INS | Nonsense Mutation | UCEC |
| 674 | F → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 806 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 806 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 820 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1119 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 965* | C → ? | 0.002288 | SNP | Nonsense Mutation | STAD |
| ? | ? → ? | 0.002033 | SNP | Missense Mutation | LUSC |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |