Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7C3M2 | RPL3 | 60S ribosomal protein L3 | Homo sapiens (Human) | 261 aa |
Protein Details: H7C3M2 (RPL3)
Protein Information
| Accession | H7C3M2 |
|---|---|
| Protein Names | 60S ribosomal protein L3 |
| Gene Symbol | RPL3 |
| Organism | Homo sapiens (Human) |
| Length | 261 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 19801377 29575903 31251020 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVCVVMAAVS11LSPASARLNP21RRIAAIPSWP31APGSHRKFSA41PRHGSLGFLP
51-10051RKRSSRHRGK61VKSFPKDDPS71KPVHLTAFLG81YKAGMTHIVR91EVDRPGSKVN
101-150101KKEVVEAVTI111VETPPMVVVG121IVGYVETPRG131LRTFKTVFAE141HISDECKRRF
151-200151YKNWHKSKKK161AFTKYCKKWQ171DEDGKKQLEK181DFSSMKKYCQ191VIRVIAHTQM
201-250201RLLPLRQKKA211HLMEIQVNGG221TVAEKLDWAR231ERLEQQVPVN241QVFGQDEMID
251-261251VIGVTKGKGY261K
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.05
|
|
| 146 | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.45
|
|
| 166 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.27
|
|
| 189 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.86
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
3
LNCaP
Specificity: 0.333
3/3 (100.0%)
3
PC3
Specificity: 0.333
3/3 (100.0%)
1
HeLa cell
Specificity: 0.111
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.111
1/1 (100.0%)
1
DU145 cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 249 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 291 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |