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UniProt ID Gene Symbol Protein Name Organism Length Action
H7C3S8 NT5DC3 5'-nucleotidase domain containing 3 Homo sapiens (Human) 122 aa

Protein Details: H7C3S8 (NT5DC3)

Protein Information
AccessionH7C3S8
Protein Names5'-nucleotidase domain containing 3
Gene SymbolNT5DC3
OrganismHomo sapiens (Human)
Length122 aa
IsoformsNo isoforms
Related PMIDs 31251020 32944167
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501XTMTWLQTLT11GLLEQMQVHR21DAESQLVLQE31WKKERKEMRE41MTKSFFNAQF
51-10051GSLFRTDQNP61TYFLRRLSRF71ADIYMASLSC81LLNYDVSHTF91YPRRTPLQHE
101-122101LPAWSERPPT111FGTPLLQEAQ121AK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
80 - - -
Deep-Palm: 0.70
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
LNCaP
Specificity: 0.667
2/2 (100.0%)
1
PC3
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
148 R → C 0.002288 SNP Missense Mutation STAD
229 C → C 0.002427 SNP Silent BLCA
305 F → C 0.001887 SNP Missense Mutation UCEC
335 F → C 0.002294 SNP Missense Mutation OV
373 F → C 0.001764 SNP Missense Mutation LUAD
403 G → C 0.005618 SNP Missense Mutation PAAD
437 G → C 0.002033 SNP Missense Mutation LUSC
492 R → C 0.002033 SNP Missense Mutation LUSC