Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7C4G8 | NT5DC2 | 5'-nucleotidase domain containing 2 | Homo sapiens (Human) | 258 aa |
Protein Details: H7C4G8 (NT5DC2)
Protein Information
| Accession | H7C4G8 |
|---|---|
| Protein Names | 5'-nucleotidase domain containing 2 |
| Gene Symbol | NT5DC2 |
| Organism | Homo sapiens (Human) |
| Length | 258 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XQDMRRLVHD11LLPPEVCSLL21NPAAIYANNE31ISLRDVEVYG41FDYDYTLAQY
51-10051ADALHPEIFS61TARDILIEHY71KSLLMKIDAF81HYVQLGTAYR91GLQPVPDEEG
101-150101PSIKQFMDIF111SLPEMALLSC121VVDYFLGHSL131EFDQAHLYKD141VTDAIRDVHV
151-200151KGLMYQWIEQ161DMEKYILRGD171ETFAVLSRLV181AHGKQLFLIT191NSPFSFVDKG
201-250201MRHMVGPDWR211QLFDVVIVQA221DKPSFFTDRR231KPFRKLDEKG241SLQWDRITRL
251-258251EKGKIYRQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 17 | - | - | - |
Deep-Palm: 0.96
|
|
| 120 | - | - | - |
Deep-Palm: 0.46
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
LNCaP
Specificity: 0.500
3/3 (100.0%)
2
PC3
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.167
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 32 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 94 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 94 | R → C | 0.001969 | SNP | Missense Mutation | LGG |
| 119 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 256 | R → C | 0.019608 | SNP | Missense Mutation | CHOL |
| 288 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 349 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 352 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 387 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 486 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |