Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
H7C519 NT5DC2 5'-nucleotidase domain containing 2 Homo sapiens (Human) 194 aa

Protein Details: H7C519 (NT5DC2)

Protein Information
AccessionH7C519
Protein Names5'-nucleotidase domain containing 2
Gene SymbolNT5DC2
OrganismHomo sapiens (Human)
Length194 aa
IsoformsNo isoforms
Related PMIDs 31251020 32944167
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501WRQLFDVVIV11QADKPSFFTD21RRKPFRKLDE31KGSLQWDRIT41RLEKGKIYRQ
51-10051GNLFDFLRLT61EWRGPRVLYF71GDHLYSDLAD81LMLRHGWRTG91AIIPELEREI
101-150101RIINTEQYMH111SLTWQQALTG121LLERMQTYQD131AESRQVLAAW141MKERQELSCL
151-194151LNYRVDFTFY161PRRTPLQHEA171PLWMDQLCTG181CMKTPFLGDM191AHIR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
149 - - -
GPS-Palm: 0.79
Deep-Palm: 0.87
178 - - -
Deep-Palm: 0.26
181 - - -
GPS-Palm: 0.79
Deep-Palm: 0.13
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
LNCaP
Specificity: 0.600
3/3 (100.0%)
2
PC3
Specificity: 0.400
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
32 R → C 0.001887 SNP Missense Mutation UCEC
94 R → C 0.003774 SNP Missense Mutation UCEC
94 R → C 0.001969 SNP Missense Mutation LGG
119 R → C 0.002506 SNP Missense Mutation COAD
256 R → C 0.019608 SNP Missense Mutation CHOL
288 R → C 0.003460 SNP Missense Mutation CESC
349 R → C 0.001887 SNP Missense Mutation UCEC
352 R → C 0.002288 SNP Missense Mutation STAD
387 R → C 0.002141 SNP Missense Mutation SKCM
486 Y → C 0.002288 SNP Missense Mutation STAD