Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7C577 | SLC33A1 | Solute carrier family 33 member … | Homo sapiens (Human) | 185 aa |
Protein Details: H7C577 (SLC33A1)
Protein Information
| Accession | H7C577 |
|---|---|
| Protein Names | Solute carrier family 33 member 1 |
| Gene Symbol | SLC33A1 |
| Organism | Homo sapiens (Human) |
| Length | 185 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501WGTVFLITTT11LVALLKKENE21VSVVKEETQG31ITDTYKLLFA41IIKMPAVLTF
51-10051CLLILTAKVT61VYSMYVSIMA71FNAKVSDPLI81GGTYMTLLNT91VSNLGGNWPS
101-150101TVALWLVDPL111TVKECVGASN121QNCRTPDAVE131LCKKLGGSCV141TALDGYYVES
151-185151IICVFIGFGW161WFFLGPKFKK171LQDEGSSSWK181CKRNN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 51 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.73
|
|
| 115 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.94
|
|
| 123 | - | - | - |
Deep-Palm: 0.93
|
|
| 132 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.94
|
| 139 | - | - | - |
Deep-Palm: 0.96
|
|
| 153 | - | - | - |
Deep-Palm: 0.07
|
|
| 181 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
PC3
Specificity: 0.750
3/3 (100.0%)
1
LNCaP
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 411 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 479 | C → S | 0.002141 | SNP | Missense Mutation | SKCM |
| 479 | C → F | 0.002976 | SNP | Missense Mutation | KIRC |
| 501 | G → _C503del | 0.002033 | DEL | In Frame Del | LUSC |
| 514 | S → C | 0.001969 | SNP | Missense Mutation | LGG |
| 522 | F → C | 0.002506 | SNP | Missense Mutation | COAD |