Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| H7C5K2 | STIM2 | Stromal interaction molecule 2 | Homo sapiens (Human) | 347 aa |
Protein Details: H7C5K2 (STIM2)
Protein Information
| Accession | H7C5K2 |
|---|---|
| Protein Names | Stromal interaction molecule 2 |
| Gene Symbol | STIM2 |
| Organism | Homo sapiens (Human) |
| Length | 347 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.949
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
37
LNCaP cells
Specificity: 0.949
37/46 (80.4%)
2
PC3 cells
Specificity: 0.051
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501EINYAKEEAC11RLRELREGAE21CELSRRQYAE31QELEQVRMAL41KKAEKEFELR
51-10051SSWSVPDALQ61KWLQLTHEVE71VQYYNIKRQN81AEMQLAIAKD91EAEKIKKKRS
101-150101TVFGTLHVAH111SSSLDEVDHK121ILEAKKALSE131LTTCLRERLF141RWQQIEKICG
151-200151FQIAHNSGLP161SLTSSLYSDH171SWVVMPRVSI181PPYPIAGGVD191DLDEDTPPIV
201-250201SQFPGTMAKP211PGSLARSSSL221CRSRRSIVPS231SPQPQRAQLA241PHAPHPSHPR
251-300251HPHHPQHTPH261SLPSPDPDIL271SVSSCPALYR281NEEEEEAIYF291SAEKQWNTRE
301-347301CAVGDSQGPH311VHGLVRFDKD321FGSYSEYERK331HWEVSRKCQT341QLQNVTP
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 10 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 21 | Prediction (High) | - | - |
| 134 | Prediction (High) | - | - |
| 149 | Prediction (Medium) | - | - |
| 221 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 318 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 329 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 433 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 433 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 516 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 597 | C → C | 0.002288 | SNP | Silent | STAD |
| 647 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 694 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |