Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| I3L161 | PLSCR3 | Phospholipid scramblase | Homo sapiens (Human) | 170 aa |
Protein Details: I3L161 (PLSCR3)
Protein Information
| Accession | I3L161 |
|---|---|
| Protein Names | Phospholipid scramblase |
| Gene Symbol | PLSCR3 |
| Organism | Homo sapiens (Human) |
| Length | 170 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 32651440 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEVQAPPGTT11IGHVLQTWHP21FLPKFSIQDA31DRQTVLRVVG41PCWTCGCGTD
51-10051TNFEVKTRDE61SRSVGRISKQ71WGGLVREALT81DADDFGLQFP91LDLDVRVKAV
101-150101LLGATFLIVS111WLPLPPPPAC121PLLSFEALCI131SWPLARGKSG141IGVVGVEVLE
151-170151LACDSQAGLA161QPDLPLTVAS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 42 | SWISSPALM DBPTM CYSMODDB | Scramblase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.69
Deep-Palm: 0.84
|
| 45 | SWISSPALM DBPTM CYSMODDB | Scramblase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.75
Deep-Palm: 0.55
|
| 47 | SWISSPALM DBPTM CYSMODDB | Scramblase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.79
Deep-Palm: 0.54
|
| 120 | - | - | - |
Deep-Palm: 0.97
|
|
| 129 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.98
|
|
| 153 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
PC3
Specificity: 0.571
4/4 (100.0%)
1
Jurkat T cell
Specificity: 0.143
1/1 (100.0%)
1
DU145 cell
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.143
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.