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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
I3L380 ABHD12 Abhydrolase domain containing 12, lysophospholipase Homo sapiens (Human) 118 aa

Protein Details: I3L380 (ABHD12)

Protein Information
Accession I3L380
Protein Names Abhydrolase domain containing 12, lysophospholipase
Gene Symbol ABHD12
Organism Homo sapiens (Human)
Length 118 aa
Isoforms No isoforms
Related PMIDs 31251020 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.971
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
34
LNCaP cells
Specificity: 0.971
34/46 (73.9%)
1
Cerebral cortex
Specificity: 0.029
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MRKRTEPVAL11EHERCAAAGS21SSSGSAAAAL31DADCRLKQNL41RLTGPAAAEP
51-10051RCAADAGMKR61ALGRRKGVWL71RLRKILFCVL81GLYIAIPFLI91KLCPGIQAKL
101-118101IFLNFGPCAP111SQLEDFLC
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
34 Prediction (High) - -
52 Prediction (Medium) - -
78 Prediction (Medium) - -
93 Prediction (Medium) - -
118 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
197 G → C 0.002545 SNP Missense Mutation GBM
323 C → S 0.002294 SNP Missense Mutation OV