Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| I3L3X5 | PLSCR3 | Phospholipid scramblase | Homo sapiens (Human) | 271 aa |
Protein Details: I3L3X5 (PLSCR3)
Protein Information
| Accession | I3L3X5 |
|---|---|
| Protein Names | Phospholipid scramblase |
| Gene Symbol | PLSCR3 |
| Organism | Homo sapiens (Human) |
| Length | 271 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 32651440 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAGYLPPKGY11APSPPPPYPV21TPGYPEPALH31PGPGQAPVPA41QVPAPAPGFA
51-10051LFPSPGPVAL61GSAAPFLPLP71GVPSGLEFLV81QIDQILIHQK91AERVETFLGW
101-150101ETCNRYELRS111GAGQPLGQAA121EESNCCARLC131CGARRPLRVR141LADPGDREVL
151-200151RLLRPLHCGC161SCCPCGLQEF171SIQDADRQTV181LRVVGPCWTC191GCGTDTNFEV
201-250201KTRDESRSVG211RISKQWGGLV221REALTDADDF231GLQFPLDLDV241RVKAVLLGAT
251-271251FLIDYMFFEK261RGGAGPSAVT271S
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 103 | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.75
Deep-Palm: 0.98
|
|
| 125 | SWISSPALM DBPTM CYSMODDB | Scramblase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.90
Deep-Palm: 0.93
|
| 126 | SWISSPALM DBPTM CYSMODDB | Scramblase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.94
Deep-Palm: 0.94
|
| 130 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.96
|
|
| 131 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.95
|
|
| 158 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.98
|
|
| 160 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.98
|
|
| 162 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.95
|
|
| 163 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.91
|
|
| 165 | - | - | - |
Deep-Palm: 0.82
|
|
| 187 | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.69
Deep-Palm: 0.85
|
|
| 190 | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.75
Deep-Palm: 0.55
|
|
| 192 | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.79
Deep-Palm: 0.54
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
PC3
Specificity: 0.308
4/4 (100.0%)
3
LNCaP
Specificity: 0.231
3/3 (100.0%)
1
Jurkat T cell
Specificity: 0.077
1/1 (100.0%)
1
DU145 cell
Specificity: 0.077
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
2
LNCaP cells (Mass)
Specificity: 0.154
2/4 (50.0%)
2
Cerebral Cortex (Mass)
Specificity: 0.154
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.