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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
I3L4N8 ACTG1 Actin gamma 1 Homo sapiens (Human) 351 aa

Protein Details: I3L4N8 (ACTG1)

Protein Information
Accession I3L4N8
Protein Names Actin gamma 1
Gene Symbol ACTG1
Organism Homo sapiens (Human)
Length 351 aa
Isoforms No isoforms
Related PMIDs 21076176 29575903 31251020 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.783
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.783
36/46 (78.3%)
6
Jurkat T cells
Specificity: 0.130
6/25 (24.0%)
4
PC3 cells
Specificity: 0.087
4/4 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEEEIAALVI11DNGSGMCKAG21FAGDDAPRAV31FPSIVGRPRH41QGVMVGMGQK
51-10051DSYVGDEAQS61KRGILTLKYP71IEHGIVTNWD81DMEKIWHHTF91YNELRVAPEE
101-150101HPVLLTEAPL111NPKAVLSLYA121SGRTTGIVMD131SGDGVTHTVP141IYEGYALPHA
151-200151ILRLDLAGRD161LTDYLMKILT171ERGYSFTTTA181EREIVRDIKE191KLCYVALDFE
201-250201QEMATAASSS211SLEKSYELPD221GQVITIGNER231FRCPEALFQP241SFLGMESCGI
251-300251HETTFNSIMK261CDVDIRKDLY271ANTVLSGGTT281MYPGIADRMQ291KEITALAPST
301-350301MKIKIIAPPE311RKYSVWIGGS321ILASLSTFQQ331MWISKQEYDE341SGPSIVHRKC
351-351351F
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
193 Experimental Prediction (Low) Actin 29575903
350 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
95 R → C 0.003460 SNP Missense Mutation CESC
218 Y → C 0.001887 SNP Missense Mutation UCEC
257 C → Y 0.001969 SNP Missense Mutation HNSC
293 L → Cfs*33 0.002033 DEL Frame Shift Del THCA
335 R → C 0.002288 SNP Missense Mutation STAD
337 Y → C 0.002506 SNP Missense Mutation COAD