Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| J3KNL1 | TSPAN4 | Tetraspanin | Homo sapiens (Human) | 204 aa |
Protein Details: J3KNL1 (TSPAN4)
Protein Information
| Accession | J3KNL1 |
|---|---|
| Protein Names | Tetraspanin |
| Gene Symbol | TSPAN4 |
| Organism | Homo sapiens (Human) |
| Length | 204 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MARACLQAVK11YLMFAFNLLF21WLGGCGVLGV31GIWLAATQGS41FATLSSSFPS
51-10051LSAANLLIIT61GAFVMAIGFV71GCLGAIKENK81CLLLTFFLLL91LLVFLLEATI
101-150101AILFFAYTDK111FRCCGVSNYT121DWFEVYNATR131VPDSCCLEFS141ESCGLHAPGT
151-200151WWKAPCYETV161KVWLQENLLA171VGIFGLCTAL181VQILGLTFAM191TMYCQVVKAD
201-204201TYCA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | Prokaryotic membrane lipoprotein lipid attachment site profile. | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.03
|
|
| 25 | Prokaryotic membrane lipoprotein lipid attachment site profile. Tetraspanin/Peripherin | - | - |
Deep-Palm: 0.56
|
|
| 72 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.97
|
|
| 81 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.98
|
|
| 113 | - | - | - |
Deep-Palm: 0.52
|
|
| 114 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.46
|
|
| 135 | - | - | - |
Deep-Palm: 0.36
|
|
| 136 | - | - | - |
Deep-Palm: 0.26
|
|
| 143 | - | - | - |
Deep-Palm: 0.13
|
|
| 156 | - | - | - |
Deep-Palm: 0.91
|
|
| 177 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.83
|
|
| 194 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.66
Deep-Palm: 0.02
|
| 203 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 46 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 228 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 81* | C → ? | 0.005618 | SNP | Nonsense Mutation | PAAD |