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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
J3KPD9 NME1-NME2 nucleoside-diphosphate kinase (EC 2.7.4.6) Homo sapiens (Human) 197 aa

Protein Details: J3KPD9 (NME1-NME2)

Protein Information
AccessionJ3KPD9
Protein Namesnucleoside-diphosphate kinase (EC 2.7.4.6)
Gene SymbolNME1-NME2
OrganismHomo sapiens (Human)
Length197 aa
IsoformsNo isoforms
Related PMIDs 31251020 36430497
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MANCERTFIA11IKPDGVQRGL21VGEIIKRFEQ31KGFRLVGLKF41MQASEDLLKE
51-10051HYVDLKDRPF61FAGLVKYMHS71GPVVAMVWEG81LNVVKTGRVM91LGETNPADSK
101-150101PGTIRGDFCI111QVGRTMANLE121RTFIAIKPDG131VQRGLVGEII141KRFEQKGFRL
151-197151VAMKFLRASE161EHLKQHYIDL171KDRPFFPGLV181KYMNSGPVVA191MEHHSWQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
4 Nucleoside diphosphate kinase-like domain superfamily - -
GPS-Palm: 0.95
Deep-Palm: 0.02
109 SWISSPALM DBPTM CYSMODDB Nucleoside diphosphate kinase
HeLa (29575903)
cerebral cortex (36430497)
GPS-Palm: 0.83
Deep-Palm: 0.81
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
LNCaP
Specificity: 0.500
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.500
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine