Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| J3KPM9 | STAT1 | Signal transducer and activator of … | Homo sapiens (Human) | 714 aa |
Protein Details: J3KPM9 (STAT1)
Protein Information
| Accession | J3KPM9 |
|---|---|
| Protein Names | Signal transducer and activator of transcription |
| Gene Symbol | STAT1 |
| Organism | Homo sapiens (Human) |
| Length | 714 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MWMSQWYELQ11QLDSKFLEQV21HQLYDDSFPM31EIRQYLAQWL41EKQDWEHAAN
51-10051DVSFATIRFH61DLLSQLDDQY71SRFSLENNFL81LQHNIRKSKR91NLQDNFQEDP
101-150101IQMSMIIYSC111LKEERKILEN121AQRFNQAQSG131NIQSTVMLDK141QKELDSKVRN
151-200151VKDKVMCIEH161EIKSLEDLQD171EYDFKCKTLQ181NREHETNGVA191KSDQKQEQLL
201-250201LKKMYLMLDN211KRKEVVHKII221ELLNVTELTQ231NALINDELVE241WKRRQQSACI
251-300251GGPPNACLDQ261LQNWFTIVAE271SLQQVRQQLK281KLEELEQKYT291YEHDPITKNK
301-350301QVLWDRTFSL311FQQLIQSSFV321VERQPCMPTH331PQRPLVLKTG341VQFTVKLRLL
351-400351VKLQELNYNL361KVKVLFDKDV371NERNTVKGFR381KFNILGTHTK391VMNMEESTNG
401-450401SLAAEFRHLQ411LKEQKNAGTR421TNEGPLIVTE431ELHSLSFETQ441LCQPGLVIDL
451-500451ETTSLPVVVI461SNVSQLPSGW471ASILWYNMLV481AEPRNLSFFL491TPPCARWAQL
501-550501SEVLSWQFSS511VTKRGLNVDQ521LNMLGEKLLG531PNASPDGLIP541WTRFCKENIN
551-600551DKNFPFWLWI561ESILELIKKH571LLPLWNDGCI581MGFISKERER591ALLKDQQPGT
601-650601FLLRFSESSR611EGAITFTWVE621RSQNGGEPDF631HAVEPYTKKE641LSAVTFPDII
651-700651RNYKVMAAEN661IPENPLKYLY671PNIDKDHAFG681KYYSRPKEAP691EPMELDGPKG
701-714701TGYIKTELIS711VSEV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 110 | - | - | - |
Deep-Palm: 0.35
|
|
| 157 | - | - | - |
Deep-Palm: 0.90
|
|
| 176 | - | - | - |
Deep-Palm: 0.71
|
|
| 249 | - | - | - |
Deep-Palm: 0.71
|
|
| 257 | - | - | - |
Deep-Palm: 0.49
|
|
| 326 | - | - | - |
Deep-Palm: 0.68
|
|
| 442 | - | - | - |
Deep-Palm: 0.92
|
|
| 494 | SWISSPALM DBPTM CYSMODDB | Signal transducer and activator of transcription linker domain |
HeLa
(29575903)
| - |
Deep-Palm: 0.92
|
| 545 | - | - | - |
Deep-Palm: 0.23
|
|
| 579 | - | - | - |
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
PC3
Specificity: 0.600
3/3 (100.0%)
1
LNCaP
Specificity: 0.200
1/1 (100.0%)
1
U937 cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 70 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 155 | C → G | 0.002506 | SNP | Missense Mutation | COAD |
| 377 | F → C | 0.002545 | SNP | Missense Mutation | GBM |
| 577 | C → Y | 0.007299 | SNP | Missense Mutation | READ |
| 649 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |