Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| J3KPM9 | STAT1 | Signal transducer and activator of … | Homo sapiens (Human) | 714 aa |
Protein Details: J3KPM9 (STAT1)
Protein Information
| Accession | J3KPM9 |
|---|---|
| Protein Names | Signal transducer and activator of transcription |
| Gene Symbol | STAT1 |
| Organism | Homo sapiens (Human) |
| Length | 714 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.706
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 0.706
12/46 (26.1%)
3
PC3 cells
Specificity: 0.176
3/4 (75.0%)
1
U937 cells
Specificity: 0.059
1/1 (100.0%)
1
Cerebral cortex
Specificity: 0.059
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MWMSQWYELQ11QLDSKFLEQV21HQLYDDSFPM31EIRQYLAQWL41EKQDWEHAAN
51-10051DVSFATIRFH61DLLSQLDDQY71SRFSLENNFL81LQHNIRKSKR91NLQDNFQEDP
101-150101IQMSMIIYSC111LKEERKILEN121AQRFNQAQSG131NIQSTVMLDK141QKELDSKVRN
151-200151VKDKVMCIEH161EIKSLEDLQD171EYDFKCKTLQ181NREHETNGVA191KSDQKQEQLL
201-250201LKKMYLMLDN211KRKEVVHKII221ELLNVTELTQ231NALINDELVE241WKRRQQSACI
251-300251GGPPNACLDQ261LQNWFTIVAE271SLQQVRQQLK281KLEELEQKYT291YEHDPITKNK
301-350301QVLWDRTFSL311FQQLIQSSFV321VERQPCMPTH331PQRPLVLKTG341VQFTVKLRLL
351-400351VKLQELNYNL361KVKVLFDKDV371NERNTVKGFR381KFNILGTHTK391VMNMEESTNG
401-450401SLAAEFRHLQ411LKEQKNAGTR421TNEGPLIVTE431ELHSLSFETQ441LCQPGLVIDL
451-500451ETTSLPVVVI461SNVSQLPSGW471ASILWYNMLV481AEPRNLSFFL491TPPCARWAQL
501-550501SEVLSWQFSS511VTKRGLNVDQ521LNMLGEKLLG531PNASPDGLIP541WTRFCKENIN
551-600551DKNFPFWLWI561ESILELIKKH571LLPLWNDGCI581MGFISKERER591ALLKDQQPGT
601-650601FLLRFSESSR611EGAITFTWVE621RSQNGGEPDF631HAVEPYTKKE641LSAVTFPDII
651-700651RNYKVMAAEN661IPENPLKYLY671PNIDKDHAFG681KYYSRPKEAP691EPMELDGPKG
701-714701TGYIKTELIS711VSEV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 110 | Prediction (High) | - | - |
| 157 | Prediction (Low) | - | - |
| 442 | Prediction (Low) | - | - |
| 494 | CYSMODDB SWISSPALM DBPTM Prediction (High) | Signal transducer and activator of transcription linker domain | - |
| 579 | Prediction (Low) | - | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 70 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 155 | C → G | 0.002506 | SNP | Missense Mutation | COAD |
| 377 | F → C | 0.002545 | SNP | Missense Mutation | GBM |
| 577 | C → Y | 0.007299 | SNP | Missense Mutation | READ |
| 649 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |