Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| J3KPS3 | ALDOA; hCG_1811258 | Fructose-bisphosphate aldolase (EC 4.1.2.13) | Homo sapiens (Human) | 368 aa |
Protein Details: J3KPS3 (ALDOA)
Protein Information
| Accession | J3KPS3 |
|---|---|
| Protein Names | Fructose-bisphosphate aldolase (EC 4.1.2.13) |
| Gene Symbol | ALDOA; hCG_1811258 |
| Organism | Homo sapiens (Human) |
| Length | 368 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.735
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.735
25/46 (54.3%)
4
PC3 cells
Specificity: 0.118
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.118
4/4 (100.0%)
1
U937 cells
Specificity: 0.029
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPYQYPALTP11EQKKELSDIA21HRIVAPGKGI31LAADESTGSI41AKRLQSIGTE
51-10051NTEENRRFYR61QLLLTADDRV71NPCIGGVILF81HETLYQKADD91GRPFPQVIKS
101-150101KGGVVGIKVD111KGVVPLAGTN121GETTTQGLDG131LSERCAQYKK141DGADFAKWRC
151-200151VLKIGEHTPS161ALAIMENANV171LARYASICQQ181VGLQNGIVPI191VEPEILPDGD
201-250201HDLKRCQYVT211EKVLAAVYKA221LSDHHIYLEG231TLLKPNMVTP241GHACTQKFSH
251-300251EEIAMATVTA261LRRTVPPAVT271GITFLSGGQS281EEEASINLNA291INKCPLLKPW
301-350301ALTFSYGRAL311QASALKAWGG321KKENLKAAQE331EYVKRALANS341LACQGKYTPS
351-368351GQAGAAASES361LFVSNHAY
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 73 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Fructose-bisphosphate aldolase class-I | - |
| 135 | Prediction (Low) | - | - |
| 178 | Prediction (Medium) | - | - |
| 294 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Fructose-bisphosphate aldolase class-I | - |
| 343 | CYSMODDB SWISSPALM DBPTM Prediction (High) | Fructose-bisphosphate aldolase class-I | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 76 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 149 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 201 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 201 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 204 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |