Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| J3KQ42 | TSPAN4 | Tetraspanin | Homo sapiens (Human) | 257 aa |
Protein Details: J3KQ42 (TSPAN4)
Protein Information
| Accession | J3KQ42 |
|---|---|
| Protein Names | Tetraspanin |
| Gene Symbol | TSPAN4 |
| Organism | Homo sapiens (Human) |
| Length | 257 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTPRSAGTSA11HGAELKRCGM21ARACLQAVKY31LMFAFNLLFW41LGGCGVLGVG
51-10051IWLAATQGSF61ATLSSSFPSL71SAANLLIITG81AFVMAIGFVG91CLGAIKENKC
101-150101LLLTFFLLLL111LVFLLEATIA121ILFFAYTDKI131DRYAQQDLKK141GLHLYGTQGN
151-200151VGLTNAWSII161QTDFRCCGVS171NYTDWFEVYN181ATRVPDSCCL191EFSESCGLHA
201-250201PGTWWKAPCY211ETVKVWLQEN221LLAVGIFGLC231TALVQILGLT241FAMTMYCQVV
251-257251KADTYCA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 18 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.93
|
|
| 24 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.86
|
|
| 44 | - | - | - |
Deep-Palm: 0.56
|
|
| 91 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.97
|
|
| 100 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.98
|
|
| 166 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.65
|
|
| 167 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.64
|
|
| 188 | - | - | - |
Deep-Palm: 0.36
|
|
| 189 | - | - | - |
Deep-Palm: 0.26
|
|
| 196 | - | - | - |
Deep-Palm: 0.13
|
|
| 209 | - | - | - |
Deep-Palm: 0.91
|
|
| 230 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.83
|
|
| 247 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.66
Deep-Palm: 0.02
|
| 256 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 46 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 228 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 81* | C → ? | 0.005618 | SNP | Nonsense Mutation | PAAD |