Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| J3KQE5 | RAN | GTP-binding nuclear protein Ran | Homo sapiens (Human) | 234 aa |
Protein Details: J3KQE5 (RAN)
Protein Information
| Accession | J3KQE5 |
|---|---|
| Protein Names | GTP-binding nuclear protein Ran |
| Gene Symbol | RAN |
| Organism | Homo sapiens (Human) |
| Length | 234 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.875
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.875
35/46 (76.1%)
4
Cerebral cortex
Specificity: 0.100
4/4 (100.0%)
1
U937 cells
Specificity: 0.025
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501RRRRLRLRRL11NCASAIFPAS21VGRARRRFWK31LVLVGDGGTG41KTTFVKRHLT
51-10051GEFEKKYVAT61LGVEVHPLVF71HTNRGPIKFN81VWDTAGQEKF91GGLRDGYYIQ
101-150101AQCAIIMFDV111TSRVTYKNVP121NWHRDLVRVC131ENIPIVLCGN141KVDIKDRKVK
151-200151AKSIVFHRKK161NLQYYDISAK171SNYNFEKPFL181WLARKLIGDP191NLEFVAMPAL
201-234201APPEVVMDPA211LAAQYEHDLE221VAQTTALPDE231DDDL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 12 | Prediction (Medium) | - | - |
| 103 | Prediction (Low) | - | - |
| 130 | CYSMODDB SWISSPALM DBPTM | Ras family | - |
| 138 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Ras family | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 85 | C → C | 0.002033 | SNP | Silent | LUSC |