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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
J3KRZ1 DDX5 DEAD-box helicase 5 Homo sapiens (Human) 166 aa

Protein Details: J3KRZ1 (DDX5)

Protein Information
Accession J3KRZ1
Protein Names DEAD-box helicase 5
Gene Symbol DDX5
Organism Homo sapiens (Human)
Length 166 aa
Isoforms No isoforms
Related PMIDs 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 1.000
36/46 (78.3%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501ERGDGPICLV11LAPTRELAQQ21VQQVAAEYCR31ACRLKSTCIY41GGAPKGPQIR
51-10051DLERGVEICI61ATPGRLIDFL71ECGKTNLRRT81TYLVLDEADR91MLDMGFEPQI
101-150101RKIVDQIRPD111RQTLMWSATW121PKEVRQLAED131FLKDYIHINI141GALELSANHN
151-166151ILQIVDVCHD161VEKDEK
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
8 Prediction (High) - -
29 Prediction (Low) - -
32 Prediction (Low) - -
38 Prediction (High) - -
59 CYSMODDB SWISSPALM DBPTM Prediction (High) - -
72 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
191 C → G 0.002427 SNP Missense Mutation BLCA
331 R → C 0.001014 SNP Missense Mutation BRCA
461 R → C 0.002141 SNP Missense Mutation SKCM
482 R → C 0.002141 SNP Missense Mutation SKCM
493 R → C 0.003460 SNP Missense Mutation CESC
497 Y → C 0.002288 SNP Missense Mutation STAD
526 F → C 0.001887 SNP Missense Mutation UCEC