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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
J3KS25 EIF4A1 ATP-dependent RNA helicase (EC 3.6.4.13) Homo sapiens (Human) 187 aa

Protein Details: J3KS25 (EIF4A1)

Protein Information
Accession J3KS25
Protein Names ATP-dependent RNA helicase (EC 3.6.4.13)
Gene Symbol EIF4A1
Organism Homo sapiens (Human)
Length 187 aa
Isoforms No isoforms
Related PMIDs 29575903 31251020 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.815
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
22
LNCaP cells
Specificity: 0.815
22/46 (47.8%)
4
PC3 cells
Specificity: 0.148
4/4 (100.0%)
1
HeLa cells
Specificity: 0.037
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSASQDSRDN11GPDGMEPEGV21IESNWNEIVD31SFDDMNLSES41LLRGIYAYGF
51-10051EKPSAIQQRA61ILPCIKGYDV71IAQAQSGTGK81TATFAISILQ91QIELDLKATQ
101-150101ALVLAPTREL111AQQIQKVVMA121LGDYMGASCH131ACIGGTNVRA141EVQKLQMEAP
151-187151HIIVGTPGRV161FDMLNRRYLS171PKYIKMFVLD181EADEMLS
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
64 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
78 S → C 0.002427 SNP Missense Mutation BLCA
141 R → C 0.001887 SNP Missense Mutation UCEC
247 R → C 0.001887 SNP Missense Mutation UCEC
319 R → C 0.002427 SNP Missense Mutation BLCA
? ? → ? 0.002141 SNP Missense Mutation SKCM