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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
J3KTA4 DDX5 Probable ATP-dependent RNA helicase DDX5 … Homo sapiens (Human) 614 aa

Protein Details: J3KTA4 (DDX5)

Protein Information
Accession J3KTA4
Protein Names Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5)
Gene Symbol DDX5
Organism Homo sapiens (Human)
Length 614 aa
Isoforms No isoforms
Related PMIDs 21076176 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.900
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.900
36/46 (78.3%)
4
Jurkat T cells
Specificity: 0.100
4/25 (16.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKAGRFEADE11GTSVRFGAPR21FGGSRAGPLS31GKKFGNPGEK41LVKKKWNLDE
51-10051LPKFEKNFYQ61EHPDLARRTA71QEVETYRRSK81EITVRGHNCP91KPVLNFYEAN
101-150101FPANVMDVIA111RQNFTEPTAI121QAQGWPVALS131GLDMVGVAQT141GSGKTLSYLL
151-200151PAIVHINHQP161FLERGDGPIC171LVLAPTRELA181QQVQQVAAEY191CRACRLKSTC
201-250201IYGGAPKGPQ211IRDLERGVEI221CIATPGRLID231FLECGKTNLR241RTTYLVLDEA
251-300251DRMLDMGFEP261QIRKIVDQIR271PDRQTLMWSA281TWPKEVRQLA291EDFLKDYIHI
301-350301NIGALELSAN311HNILQIVDVC321HDVEKDEKLI331RLMEEIMSEK341ENKTIVFVET
351-400351KRRCDELTRK361MRRDGWPAMG371IHGDKSQQER381DWVLNEFKHG391KAPILIATDV
401-450401ASRGLDVEDV411KFVINYDYPN421SSEDYIHRIG431RTARSTKTGT441AYTFFTPNNI
451-500451KQVSDLISVL461REANQAINPK471LLQLVEDRGS481GRSRGRGGMK491DDRRDRYSAG
501-550501KRGGFNTFRD511RENYDRGYSS521LLKRDFGAKT531QNGVYSAANY541TNGSFGSNFV
551-600551SAGIQTSFRT561GNPTGTYQNG571YDSTQQYGSN581VPNMHNGMNQ591QAYAYPATAA
601-614601APMIGYPMPT611GYSQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
170 Prediction (High) - -
191 Prediction (Low) - -
194 Prediction (Low) - -
200 Prediction (High) - -
221 CYSMODDB SWISSPALM DBPTM Prediction (High) - -
234 Prediction (High) - -
354 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
191 C → G 0.002427 SNP Missense Mutation BLCA
331 R → C 0.001014 SNP Missense Mutation BRCA
461 R → C 0.002141 SNP Missense Mutation SKCM
482 R → C 0.002141 SNP Missense Mutation SKCM
493 R → C 0.003460 SNP Missense Mutation CESC
497 Y → C 0.002288 SNP Missense Mutation STAD
526 F → C 0.001887 SNP Missense Mutation UCEC