Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| J3QQV2 | SLC16A3 | Solute carrier family 16 member … | Homo sapiens (Human) | 417 aa |
Protein Details: J3QQV2 (SLC16A3)
Protein Information
| Accession | J3QQV2 |
|---|---|
| Protein Names | Solute carrier family 16 member 3 |
| Gene Symbol | SLC16A3 |
| Organism | Homo sapiens (Human) |
| Length | 417 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGGAVVDEGP11TGVKAPDGGW21GWAVLFGCFV31ITGFSYAFPK41AVSVFFKELI
51-10051QEFGIGYSDT61AWISSILLAM71LYGTGLGLAL81NFQPSLIMLN91RYFSKRRPMA
101-150101NGLAAAGSPV111FLCALSPLGQ121LLQDRYGWRG131GFLILGGLLL141NCCVCAALMR
151-200151PLVVTAQPGS161GPPRPSRRLL171DLSVFRDRGF181VLYAVAASVM191VLGLFVPPVF
201-250201VVSYAKDLGV211PDTKAAFLLT221ILGFIDIFAR231PAAGFVAGLG241KVRPYSVYLF
251-300251SFSMFFNGLA261DLAGSTAGDY271GGLVVFCIFF281GISYGMVGAL291QFEVLMAIVG
301-350301THKFSSAIGL311VLLMEAVAVL321VGPPSGGKLL331DATHVYMYVF341ILAGAEVLTS
351-400351SLILLLGNFF361CIRKKPKEPQ371PEVAAAEEEK381LHKPPADSGV391DLREVEHFLK
401-417401AEPEKNGEVV411HTPETSV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 28 | - | - | - |
Deep-Palm: 0.76
|
|
| 113 | SWISSPALM DBPTM CYSMODDB | Major Facilitator Superfamily |
HeLa
(29575903)
| - |
GPS-Palm: 0.74
Deep-Palm: 0.97
|
| 142 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.94
|
|
| 143 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.97
|
|
| 145 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.97
|
|
| 277 | - | - | - |
Deep-Palm: 0.89
|
|
| 361 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
PC3
Specificity: 0.800
4/4 (100.0%)
1
HeLa cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 84 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 293 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |
| 81* | C → ? | 0.001764 | SNP | Nonsense Mutation | LUAD |