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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
J3QSF1 DDX5 DEAD-box helicase 5 Homo sapiens (Human) 153 aa

Protein Details: J3QSF1 (DDX5)

Protein Information
AccessionJ3QSF1
Protein NamesDEAD-box helicase 5
Gene SymbolDDX5
OrganismHomo sapiens (Human)
Length153 aa
IsoformsNo isoforms
Related PMIDs 31251020 32944167
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501XRGVEICIAT11PGRLIDFLEC21GKTNLRRTTY31LVLDEADRML41DMGFEPQIRK
51-10051IVDQIRPDRQ61TLMWSATWPK71EVRQLAEDFL81KDYIHINIGA91LELSANHNIL
101-150101QIVDVCHDVE111KDEKLIRLME121EIMSEKENKT131IVFVETKRRC141DELTRKMRRD
151-153151GYV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
7 SWISSPALM DBPTM CYSMODDB P-loop containing nucleoside triphosphate hydrolase -
cerebral cortex (36430497)
GPS-Palm: 0.96
Deep-Palm: 0.08
20 DEAD/DEAH box helicase domain P-loop containing nucleoside triphosphate hydrolase Helicase superfamily 1/2, ATP-binding domain ATP-DEPENDENT RNA HELICASE DBP3 - -
GPS-Palm: 0.92
Deep-Palm: 0.97
106 - - -
Deep-Palm: 0.48
140 - - -
GPS-Palm: 0.82
Deep-Palm: 0.20
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
LNCaP
Specificity: 0.500
3/3 (100.0%)
3
PC3
Specificity: 0.500
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
191 C → G 0.002427 SNP Missense Mutation BLCA
331 R → C 0.001014 SNP Missense Mutation BRCA
461 R → C 0.002141 SNP Missense Mutation SKCM
482 R → C 0.002141 SNP Missense Mutation SKCM
493 R → C 0.003460 SNP Missense Mutation CESC
497 Y → C 0.002288 SNP Missense Mutation STAD
526 F → C 0.001887 SNP Missense Mutation UCEC