Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| J3QT27 | PCBP3 | Poly(rC) binding protein 3 | Homo sapiens (Human) | 322 aa |
Protein Details: J3QT27 (PCBP3)
Protein Information
| Accession | J3QT27 |
|---|---|
| Protein Names | Poly(rC) binding protein 3 |
| Gene Symbol | PCBP3 |
| Organism | Homo sapiens (Human) |
| Length | 322 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501PQPQFGRRME11SKVSEGGLNV21TLTIRLLMHG31KEVGSIIGKK41GETVKKMREE
51-10051SGARINISEG61NCPERIVTIT71GPTDAIFKAF81AMIAYKFEED91IINSMSNSPA
101-150101TSKPPVTLRL111VVPASQCGSL121IGKGGSKIKE131IRESTGAQVQ141VAGDMLPNST
151-200151ERAVTISGTP161DAIIQCVKQI171CVVMLEAYTI181QGQYAIPHPD191QLTKLHQLAM
201-250201QQTPFPPLGQ211TNPAFPGEKL221PLHSSEEAQN231LMGQSSGLDA241SPPASTHELT
251-300251IPNDLIGCII261GRQGTKINEI271RQMSGAQIKI281ANATEGSSER291QITITGTPAN
301-322301ISLAQYLINA311RLTSEVTGMG321TL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 62 | SWISSPALM DBPTM CYSMODDB | KH domain | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
Deep-Palm: 0.93
|
| 117 | SWISSPALM DBPTM CYSMODDB | KH domain | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.93
Deep-Palm: 0.98
|
| 166 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.63
|
|
| 171 | - | - | - |
Deep-Palm: 0.19
|
|
| 258 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.86
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.800
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 72 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 190 | C → C | 0.005618 | SNP | Silent | PAAD |
| 221 | F → C | 0.003559 | SNP | Missense Mutation | KIRP |
| 311 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 339 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 190* | C → ? | 0.002747 | SNP | Nonsense Mutation | LIHC |