Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| K7EIT4 | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein … | Homo sapiens (Human) | 109 aa |
Protein Details: K7EIT4 (YWHAE)
Protein Information
| Accession | K7EIT4 |
|---|---|
| Protein Names | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon |
| Gene Symbol | YWHAE |
| Organism | Homo sapiens (Human) |
| Length | 109 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XMVESMKKVA11GMDVELTVEE21RNLLSVAYKN31VIGARRASWR41IISSIEQKEE
51-10051NKGGEDKLKM61IREYRQMVET71ELKLICCDIL81DVLDKHLIPA91ANTGWQKQLL
101-109101MMQLQNWIR
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 76 | SWISSPALM DBPTM CYSMODDB | 14-3-3 protein |
HeLa
(29575903)
|
cerebral cortex
(36430497)
Unknown
(32651440)
|
GPS-Palm: 0.87
Deep-Palm: 0.90
|
| 77 | SWISSPALM DBPTM CYSMODDB | 14-3-3 protein |
HeLa
(29575903)
|
cerebral cortex
(36430497)
Unknown
(32651440)
|
GPS-Palm: 0.84
Deep-Palm: 0.88
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
PC3
Specificity: 0.400
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
2
LNCaP
Specificity: 0.200
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 152 | Y → C | 0.002427 | SNP | Missense Mutation | BLCA |