Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| K7EIT4 | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein … | Homo sapiens (Human) | 109 aa |
Protein Details: K7EIT4 (YWHAE)
Protein Information
| Accession | K7EIT4 |
|---|---|
| Protein Names | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon |
| Gene Symbol | YWHAE |
| Organism | Homo sapiens (Human) |
| Length | 109 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.857
24/46 (52.2%)
4
PC3 cells
Specificity: 0.143
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501XMVESMKKVA11GMDVELTVEE21RNLLSVAYKN31VIGARRASWR41IISSIEQKEE
51-10051NKGGEDKLKM61IREYRQMVET71ELKLICCDIL81DVLDKHLIPA91ANTGWQKQLL
101-109101MMQLQNWIR
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 76 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | 14-3-3 protein | - |
| 77 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | 14-3-3 protein | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 152 | Y → C | 0.002427 | SNP | Missense Mutation | BLCA |