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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
K7EJ44 PFN1; hCG_32691 Profilin Homo sapiens (Human) 104 aa

Protein Details: K7EJ44 (PFN1)

Protein Information
Accession K7EJ44
Protein Names Profilin
Gene Symbol PFN1; hCG_32691
Organism Homo sapiens (Human)
Length 104 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.750
24/46 (52.2%)
4
PC3 cells
Specificity: 0.125
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.125
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGAWFLFQPA11EVGVLVGKDR21SSFYVNGLTL31GGQKCSVIRD41SLLQDGEFSM
51-10051DLRTKSTGGA61PTFNVTVTKT71DKTLVLLMGK81EGVHGGLINK91KCYEMASHLR
101-104101RSQY
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
35 Prediction (Low) - -
92 CYSMODDB SWISSPALM DBPTM Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
17 C → _D27del 0.002288 DEL In Frame Del STAD
? ? → ? 0.002427 SNP Missense Mutation BLCA