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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
K7EJ68 ACAA2 Acetyl-CoA acyltransferase 2 Homo sapiens (Human) 124 aa

Protein Details: K7EJ68 (ACAA2)

Protein Information
AccessionK7EJ68
Protein NamesAcetyl-CoA acyltransferase 2
Gene SymbolACAA2
OrganismHomo sapiens (Human)
Length124 aa
IsoformsNo isoforms
Related PMIDs 32944167 36430497
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGNVLQSSSD11AIYLARHVGL21RVGIPKETPA31LTINRLCGSG41FQSIVNGCQE
51-10051ICVKEAEVVL61CGGTESMSQA71PYCVRNVRFG81TKLGSDIKLE91DSLWVSLTDQ
101-124101HVQLPMAMTA111ENLAVKHKIS121REEC
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
37 SWISSPALM DBPTM CYSMODDB Thiolase, N-terminal Thiolase-like Thiolase, acyl-enzyme intermediate active site ACETYL-COA C-ACYLTRANSFERASE Thiolase N-terminal domain -
cerebral cortex (36430497)
GPS-Palm: 0.88
Deep-Palm: 0.96
48 SWISSPALM DBPTM CYSMODDB Thiolase, N-terminal Thiolase-like ACETYL-COA C-ACYLTRANSFERASE Thiolase N-terminal domain -
cerebral cortex (36430497)
Deep-Palm: 0.88
52 SWISSPALM DBPTM CYSMODDB Thiolase N-terminal domain -
cerebral cortex (36430497)
Deep-Palm: 0.85
61 - -
cerebral cortex (36430497)
Deep-Palm: 0.79
73 - -
cerebral cortex (36430497)
GPS-Palm: 0.91
Deep-Palm: 0.96
124 - - -
GPS-Palm: 0.92
Deep-Palm: 0.02
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
cerebral cortex
Specificity: 0.667
4/4 (100.0%)
2
PC3
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
76 R → C 0.002288 SNP Missense Mutation STAD
371 R → C 0.001969 SNP Missense Mutation LGG