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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
K7EJJ4 SCAMP4 Secretory carrier-associated membrane protein (Secretory … Homo sapiens (Human) 57 aa

Protein Details: K7EJJ4 (SCAMP4)

Protein Information
AccessionK7EJJ4
Protein NamesSecretory carrier-associated membrane protein (Secretory carrier membrane protein)
Gene SymbolSCAMP4
OrganismHomo sapiens (Human)
Length57 aa
IsoformsNo isoforms
Related PMIDs 19801377 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSEKENNFPP11LPKFIPVKPC21FYQNFSDEIP31VEHQVLVKRI41YRLWMFYCAT
51-5751LGVNLIA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
20 SWISSPALM DBPTM CYSMODDB SCAMP family SCAMP
HeLa (29575903)
-
GPS-Palm: 0.85
Deep-Palm: 0.81
48 - - -
GPS-Palm: 0.77
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
cerebral cortex
Specificity: 0.333
1/1 (100.0%)
1
DU145 cell
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.333
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
48 C → C 0.017544 SNP Silent UCS
190 W → C 0.002427 SNP Missense Mutation BLCA