Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| K7EJV8 | GALNT1 | polypeptide N-acetylgalactosaminyltransferase (EC 2.4.1.41) | Homo sapiens (Human) | 387 aa |
Protein Details: K7EJV8 (GALNT1)
Protein Information
| Accession | K7EJV8 |
|---|---|
| Protein Names | polypeptide N-acetylgalactosaminyltransferase (EC 2.4.1.41) |
| Gene Symbol | GALNT1 |
| Organism | Homo sapiens (Human) |
| Length | 387 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MRKFAYCKVV11LATSLIWVLL21DMFLLLYFSE31CNKCDEKKER41GLPAGDVLEP
51-10051VQKPHEGPGE61MGKPVVIPKE71DQEKMKEMFK81INQFNLMASE91MIALNRSLPD
101-150101VRLEGCKTKV111YPDNLPTTSV121VIVFHNEAWS131TLLRTVHSVI141NRSPRHMIEE
151-200151IVLVDDASER161DFLKRPLESY171VKKLKVPVHV181IRMEQRSGLI191RARLKGAAVS
201-250201KGQVITFLDA211HCECTVGWLE221PLLARIKHDR231RTVVCPIIDV241ISDDTFEYMA
251-300251GSDMTYGGFN261WKLNFRWYPV271PQREMDRRKG281DRTLPVRTPT291MAGGLFSIDR
301-350301DYFQEIGTYD311AGMDIWGGEN321LEISFRIWQC331GGTLEIVTCS341HVGHVFRKAT
351-387351PYTFPGGTGQ361IINKNNRRLA371EVWMDEFKNF381FYIISPG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 7 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.92
Deep-Palm: 0.02
|
| 31 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.89
|
|
| 34 | - | - | - |
Deep-Palm: 0.90
|
|
| 106 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.94
|
|
| 212 | - | - | - |
Deep-Palm: 0.91
|
|
| 214 | - | - | - |
Deep-Palm: 0.85
|
|
| 235 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.71
|
|
| 330 | - | - | - |
Deep-Palm: 0.13
|
|
| 339 | - | - | - |
Deep-Palm: 0.27
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
LNCaP
Specificity: 0.500
3/3 (100.0%)
2
PC3
Specificity: 0.333
2/2 (100.0%)
1
HeLa cell
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 142 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 212 | C → F | 0.002033 | SNP | Missense Mutation | LUSC |
| 212 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 235 | C → C | 0.001887 | SNP | Silent | UCEC |
| 330 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 352 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 459 | C → C | 0.001887 | SNP | Silent | UCEC |
| 497 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |
| 523 | C → C | 0.001887 | SNP | Silent | UCEC |