Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| K7EK04 | PLEKHH3 | Pleckstrin homology, MyTH4 and FERM … | Homo sapiens (Human) | 206 aa |
Protein Details: K7EK04 (PLEKHH3)
Protein Information
| Accession | K7EK04 |
|---|---|
| Protein Names | Pleckstrin homology, MyTH4 and FERM domain containing H3 |
| Gene Symbol | PLEKHH3 |
| Organism | Homo sapiens (Human) |
| Length | 206 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
21
LNCaP cells
Specificity: 1.000
21/46 (45.7%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPLPGGLWWL11LCCRRGFTLL21HRDYGDGELS31GDGDEDEDEE41TFELRTPSPA
51-10051GGGRGGSVEE61GKMRRRGCLG71AWQNELTSPV81SKMGKLRPGD91GKRLAQGSTG
101-150101PLEVTLTQPV111RSGPVSNRLQ121SWEETWSLIP131EKGLPEDDPD141IVVKGWLYRE
151-200151PRGGGARPWL161PPRRAWFVLT171RDSLDQFSSS181GKGARRLGSL191VLTSLCSVTG
201-206201PERRRK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 12 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 13 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 68 | Prediction (Medium) | - | - |
| 196 | Prediction (High) | - | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 189 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 516 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 757 | S → C | 0.002288 | SNP | Missense Mutation | STAD |