Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| K7EKW9 | FLOT2 | Flotillin | Homo sapiens (Human) | 249 aa |
Protein Details: K7EKW9 (FLOT2)
Protein Information
| Accession | K7EKW9 |
|---|---|
| Protein Names | Flotillin |
| Gene Symbol | FLOT2 |
| Organism | Homo sapiens (Human) |
| Length | 249 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
4
PC3 cells
Specificity: 0.667
4/4 (100.0%)
1
HeLa cells
Specificity: 0.167
1/1 (100.0%)
1
Cerebral cortex
Specificity: 0.167
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501XLSLEVMTIL11CRCENIETSE21GVPLFVTGVA31QVKIMTEKEL41LAVACEQFLG
51-10051TLTVEQIYQD61RDQFAKLVRE71VAAPDVGRMG81IEILSFTIKD91VYDKVDYLSS
101-150101LGKTQTAVVQ111RDADIGVAEA121ERDAGIREAE131CKKEMLDVKF141MADTKIADSK
151-200151RAFELQKSAF161SEEVNIKTAE171AQLAYELQGA181REQQKIRQEE191IEIEVVQRKK
201-249201QIAVEAQEIL211RTDKELIATV221RRPAEAEAHR231IQQIAEGEKV241KQVLLAQAE
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 11 | Prediction (Low) | - | - |
| 131 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 55 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 191 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 247 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 287 | R → C | 0.002288 | SNP | Missense Mutation | STAD |