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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
K7ELF0 CPD Carboxypeptidase D Homo sapiens (Human) 40 aa

Protein Details: K7ELF0 (CPD)

Protein Information
AccessionK7ELF0
Protein NamesCarboxypeptidase D
Gene SymbolCPD
OrganismHomo sapiens (Human)
Length40 aa
IsoformsNo isoforms
Related PMIDs 19137006 32944167
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-401XVGTELLLAL11AEFLCLNYKK21NPAVTQMGER31ELKRKTVLQK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
15 - - -
GPS-Palm: 0.94
Deep-Palm: 0.98
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
PC3
Specificity: 0.667
4/4 (100.0%)
2
Jurkat T cell
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
288 F → C 0.002545 SNP Missense Mutation GBM
704 A → Cfs*15 0.001014 INS Frame Shift Ins BRCA
739 W → C 0.002545 SNP Missense Mutation GBM
988 R → C 0.002141 SNP Missense Mutation SKCM
1049 C → S 0.002427 SNP Missense Mutation BLCA
1184 C → C 0.002141 SNP Silent SKCM
1206 S → C 0.002427 SNP Missense Mutation BLCA
1218 F → C 0.001887 SNP Missense Mutation UCEC
1246 G → C 0.002506 SNP Missense Mutation COAD
1321 C → G 0.002288 SNP Missense Mutation STAD
1323 C → C 0.001764 SNP Silent LUAD
1349 R → C 0.002141 SNP Missense Mutation SKCM
1376 Y → C 0.001764 SNP Missense Mutation LUAD
1323* C → ? 0.002545 SNP Nonsense Mutation GBM