Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| K7EM90 | ENO1 | phosphopyruvate hydratase (EC 4.2.1.11) (2-phospho-D-glycerate … | Homo sapiens (Human) | 195 aa |
Protein Details: K7EM90 (ENO1)
Protein Information
| Accession | K7EM90 |
|---|---|
| Protein Names | phosphopyruvate hydratase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) |
| Gene Symbol | ENO1 |
| Organism | Homo sapiens (Human) |
| Length | 195 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSILKIHARE11IFDSRGNPTV21EVDLFTSKGL31FRAAVPSGAS41TGIYEALELR
51-10051DNDKTRYMGK61GVSKAVEHIN71KTIAPALVSK81KLNVTEQEKI91DKLMIEMDGT
101-150101ENKSKFGANA111ILGVSLAVCK121AGAVEKGVPL131YRHIADLAGN141SEVILPVPAF
151-195151NVINGGSHAG161NKLAMQEFMI171LPVGAANFRE181AMRIGAEVYH191NLKNV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 119 | SWISSPALM DBPTM CYSMODDB | Enolase N-terminal domain |
HeLa
(29575903)
|
Unknown
(32651440)
cerebral cortex
(36430497)
|
GPS-Palm: 0.89
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
cerebral cortex
Specificity: 0.571
4/4 (100.0%)
2
LNCaP
Specificity: 0.286
2/2 (100.0%)
1
HeLa cell
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 130 | L → Cfs*40 | 0.002288 | DEL | Frame Shift Del | STAD |
| 399 | C → C | 0.002288 | SNP | Silent | STAD |