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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
K7EME0 ACAA2 Acetyl-CoA acyltransferase 2 Homo sapiens (Human) 342 aa

Protein Details: K7EME0 (ACAA2)

Protein Information
Accession K7EME0
Protein Names Acetyl-CoA acyltransferase 2
Gene Symbol ACAA2
Organism Homo sapiens (Human)
Length 342 aa
Isoforms No isoforms
Related PMIDs 29575903 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
2
PC3 cells
Specificity: 0.667
2/4 (50.0%)
1
HeLa cells
Specificity: 0.333
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGNVLQSSSD11AIYLARHVGL21RVGIPKETPA31LTINRLCGSG41FQSIVNGCQE
51-10051ICVKEAEVVL61CGGTESMSQA71PYCVRNVRFG81TKLGSDIKLE91DSLWVSLTDQ
101-150101HVQLPMAMTA111ENLAVKHKIS121REECDKYALQ131SQQRWKAAND141AGYFNDEMAP
151-200151IEVKTKKGKQ161TMQVDEHARP171QTTLEQLQKL181PPVFKKDGTV191TAGNASGVAD
201-250201GAGAVIIASE211DAVKKHNFTP221LARIVGYFVS231GCDPSIMGIG241PVPAISGALK
251-300251KAGLSLKDMD261LVEVNEAFAP271QYLAVERSLD281LDISKTNVNG291GAIALGHPLG
301-342301GSGSRITAHL311VHELRRRGGK321YAVGSACIGG331GQGIAVIIQS341TA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
37 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Thiolase N-terminal domain -
73 Prediction (High) - -
124 Experimental Thiolase N-terminal domain 29575903
232 Prediction (Low) - -
327 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
76 R → C 0.002288 SNP Missense Mutation STAD
371 R → C 0.001969 SNP Missense Mutation LGG