Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| K7EMM6 | USP36 | Ubiquitin specific peptidase 36 | Homo sapiens (Human) | 259 aa |
Protein Details: K7EMM6 (USP36)
Protein Information
| Accession | K7EMM6 |
|---|---|
| Protein Names | Ubiquitin specific peptidase 36 |
| Gene Symbol | USP36 |
| Organism | Homo sapiens (Human) |
| Length | 259 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
8
LNCaP cells
Specificity: 0.800
8/46 (17.4%)
2
PC3 cells
Specificity: 0.200
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MILYWSPKYF11RAPGVWEVPW21LDRQTQATTL31VHQIFGGYLR41SRVKCSVCKS
51-10051VSDTYDPYLD61VALEIRQAAN71IVRALELFVK81ADVLSGENAY91MCAKCKKKVP
101-150101ASKRFTIHRT111SNVLTLSLKR121FANFSGGKIT131KDVGYPEFLN141IRPYMSQNNG
151-200151DPVMYGLYAV161LVHSGYSCHA171GHYYCYVKAS181NGQWYQMNDS191LVHSSNVKVV
201-250201LNQQAYVLFY211LRIPGSKKSP221EGLISRTGSS231SLPGRPSVIP241DHSKKNIGNG
251-259251IISSPLTGK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 45 | Prediction (Low) | - | - |
| 48 | Prediction (Low) | - | - |
| 92 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 95 | Prediction (Medium) | - | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 119 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 157 | R → C | 0.005587 | SNP | Missense Mutation | PCPG |
| 202 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 314 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 638 | C → C | 0.001887 | SNP | Silent | UCEC |
| 994 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |
| 1006 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1122 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 1122 | R → C | 0.002294 | SNP | Missense Mutation | OV |