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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
K7EMM6 USP36 Ubiquitin specific peptidase 36 Homo sapiens (Human) 259 aa

Protein Details: K7EMM6 (USP36)

Protein Information
AccessionK7EMM6
Protein NamesUbiquitin specific peptidase 36
Gene SymbolUSP36
OrganismHomo sapiens (Human)
Length259 aa
IsoformsNo isoforms
Related PMIDs 32944167
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MILYWSPKYF11RAPGVWEVPW21LDRQTQATTL31VHQIFGGYLR41SRVKCSVCKS
51-10051VSDTYDPYLD61VALEIRQAAN71IVRALELFVK81ADVLSGENAY91MCAKCKKKVP
101-150101ASKRFTIHRT111SNVLTLSLKR121FANFSGGKIT131KDVGYPEFLN141IRPYMSQNNG
151-200151DPVMYGLYAV161LVHSGYSCHA171GHYYCYVKAS181NGQWYQMNDS191LVHSSNVKVV
201-250201LNQQAYVLFY211LRIPGSKKSP221EGLISRTGSS231SLPGRPSVIP241DHSKKNIGNG
251-259251IISSPLTGK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
45 Papain-like cysteine peptidase superfamily Cysteine proteinases - -
GPS-Palm: 0.75
Deep-Palm: 0.16
48 Cysteine proteinases - -
GPS-Palm: 0.73
Deep-Palm: 0.35
92 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.85
Deep-Palm: 0.70
95 - - -
GPS-Palm: 0.84
Deep-Palm: 0.39
168 - - -
Deep-Palm: 0.02
175 - - -
Deep-Palm: 0.02
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
PC3
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
119 R → C 0.002288 SNP Missense Mutation STAD
157 R → C 0.005587 SNP Missense Mutation PCPG
202 R → C 0.001969 SNP Missense Mutation HNSC
314 R → C 0.001887 SNP Missense Mutation UCEC
638 C → C 0.001887 SNP Silent UCEC
994 C → Y 0.002288 SNP Missense Mutation STAD
1006 R → C 0.001887 SNP Missense Mutation UCEC
1122 R → C 0.001764 SNP Missense Mutation LUAD
1122 R → C 0.002294 SNP Missense Mutation OV