Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| K7EP56 | AFG3L2 | AFG3 like matrix AAA peptidase … | Homo sapiens (Human) | 209 aa |
Protein Details: K7EP56 (AFG3L2)
Protein Information
| Accession | K7EP56 |
|---|---|
| Protein Names | AFG3 like matrix AAA peptidase subunit 2 |
| Gene Symbol | AFG3L2 |
| Organism | Homo sapiens (Human) |
| Length | 209 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 31251020 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501XVGPGEQPCL11RTGDIPWDDK21DFRMFFLWTA31LFWGGVMFYL41LLKRSGREIT
51-10051WKDFVNNYLS61KGVVDRLEVV71NKRFVRVTFT81PGKTPVDGQY91VWFNIGSVDT
101-150101FERNLETLQQ111ELGIEGENRV121PVVYIAESDG131SFLLSMLPTV141LIIAFLLYTI
151-200151RRGPAGIGRT161GRGMGGLFSV171GETTAKVLKD181EIDVKFKDVA191GCEEAKLEIM
201-209201EFVNFLKNP
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 9 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.03
|
|
| 192 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.87
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
2
PC3
Specificity: 0.400
2/2 (100.0%)
1
frontal cortex
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 106 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 468 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |