Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| K7ER88 | ACAA2 | Acetyl-CoA acyltransferase 2 | Homo sapiens (Human) | 72 aa |
Protein Details: K7ER88 (ACAA2)
Protein Information
| Accession | K7ER88 |
|---|---|
| Protein Names | Acetyl-CoA acyltransferase 2 |
| Gene Symbol | ACAA2 |
| Organism | Homo sapiens (Human) |
| Length | 72 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGNVLQSSSD11AIYLARHVGL21RVGIPKETPA31LTINRLCGSG41FQSIVNGCQE
51-7251ICVKEAEVVL61CGGTESMSQA71PY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 37 | SWISSPALM DBPTM CYSMODDB | Thiolase, N-terminal Thiolase-like Thiolase, acyl-enzyme intermediate active site ACETYL-COA C-ACYLTRANSFERASE Thiolase N-terminal domain | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.88
Deep-Palm: 0.96
|
| 48 | SWISSPALM DBPTM CYSMODDB | Thiolase, N-terminal Thiolase-like ACETYL-COA C-ACYLTRANSFERASE Thiolase N-terminal domain | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.88
|
| 52 | SWISSPALM DBPTM CYSMODDB | Thiolase N-terminal domain | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.85
|
| 61 | - | - | - |
Deep-Palm: 0.21
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
cerebral cortex
Specificity: 0.667
4/4 (100.0%)
2
PC3
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 76 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 371 | R → C | 0.001969 | SNP | Missense Mutation | LGG |