Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| K7ESE6 | G6PC3 | glucose-6-phosphatase (EC 3.1.3.9) | Homo sapiens (Human) | 243 aa |
Protein Details: K7ESE6 (G6PC3)
Protein Information
| Accession | K7ESE6 |
|---|---|
| Protein Names | glucose-6-phosphatase (EC 3.1.3.9) |
| Gene Symbol | G6PC3 |
| Organism | Homo sapiens (Human) |
| Length | 243 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MESTLGAGIV11IAEALQNQLA21WLENVWLWIT31FLGDPKILFL41FYFPAAYYAS
51-10051RRVGIAVLWI61SLITEWLNLI71FKWFLFGDRP81FWWVHESGYY91SQAPAQVATR
101-150101ARSRWVRVMP111SLAYCTFLLA121VGLSRIFILA131HFPHQVLAGL141ITGAVLGWLM
151-200151TPRVPMEREL161SFYGLTALAL171MLGTSLIYWT181LFTLGLDLSW191SISLAFKWCE
201-243201RPEWIHVDSR211PFASLSRDSG221AALGLGIALH231SPCYAQVRRA241QLG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 115 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.96
|
|
| 199 | - | - | - |
Deep-Palm: 0.89
|
|
| 233 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.91
Deep-Palm: 0.45
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
LNCaP cells (Mass)
Specificity: 0.333
1/4 (25.0%)
1
Cerebral Cortex (Mass)
Specificity: 0.333
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 26 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 66 | W → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 274 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |