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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
K7ESG8 ACLY ATP citrate lyase Homo sapiens (Human) 109 aa

Protein Details: K7ESG8 (ACLY)

Protein Information
Accession K7ESG8
Protein Names ATP citrate lyase
Gene Symbol ACLY
Organism Homo sapiens (Human)
Length 109 aa
Isoforms No isoforms
Related PMIDs 29575903 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.862
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.862
25/46 (54.3%)
3
PC3 cells
Specificity: 0.103
3/4 (75.0%)
1
HeLa cells
Specificity: 0.034
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSAKAISEQT11GKELLYKFIC21TTSAIQNRFK31YARVTPDTDW41ARLLQDHPWL
51-10051LSQNLVVKPD61QLIKRRGKLG71LVGVNLTLDG81VKSWLKPRLG91QEATVGKATG
101-109101FLKNFLIEP
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
20 CYSMODDB SWISSPALM DBPTM Prediction (High) ATP-citrate synthase ATP-grasp domain -
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
20 C → C 0.002288 SNP Silent STAD
184 F → C 0.001887 SNP Missense Mutation UCEC
576 R → C 0.002033 SNP Missense Mutation LUSC
653 R → C 0.002506 SNP Missense Mutation COAD
728 C → Y 0.001887 SNP Missense Mutation UCEC
887 C → Y 0.001887 SNP Missense Mutation UCEC
893 C → Y 0.002747 SNP Missense Mutation LIHC
1033 F → C 0.001887 SNP Missense Mutation UCEC