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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
K7ESM5 TUBB6 Tubulin beta chain Homo sapiens (Human) 338 aa

Protein Details: K7ESM5 (TUBB6)

Protein Information
Accession K7ESM5
Protein Names Tubulin beta chain
Gene Symbol TUBB6
Organism Homo sapiens (Human)
Length 338 aa
Isoforms No isoforms
Related PMIDs 21076176 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.875
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.875
35/46 (76.1%)
4
Jurkat T cells
Specificity: 0.100
4/25 (16.0%)
1
PC3 cells
Specificity: 0.025
1/4 (25.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MREIVHIQAG11QCGNQIGTKF21WEVISDEHGI31DPAGGYVGDS41ALQLERINVY
51-10051YNESSCQTGA61GNNWAKGHYT71EGAELVDAVL81DVVRKECEHC91DCLQGFQLTH
101-150101SLGGGTGSGM111GTLLISKIRE121EFPDRIMNTF131SVMPSPKVSD141TVVEPYNATL
151-200151SVHQLVENTD161ETYCIDNEAL171YDICFRTLKL181TTPTYGDLNH191LVSATMSGVT
201-250201TSLRFPGQLN211ADLRKLAVNM221VPFPRLHFFM231PGFAPLTSRG241SQQYRALTVP
251-300251ELTQQMFDAR261NMMAACDPRH271GRYLTVATVF281RGPMSMKEVD291EQMLAIQSKN
301-338301SSYFVEWIPN311NVKVAVCDIP321PRGLKMASTF331IGNSTAIQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
174 Prediction (Medium) - -
266 CYSMODDB SWISSPALM DBPTM Prediction (High) Tubulin C-terminal domain -
317 Prediction (High) - -
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
146 G → C 0.001764 SNP Missense Mutation LUAD
153 S → C 0.002033 SNP Missense Mutation LUSC
201 C → S 0.001764 SNP Missense Mutation LUAD
241 R → C 0.002033 SNP Missense Mutation LUSC
244 G → C 0.002506 SNP Missense Mutation COAD
251 R → C 0.002506 SNP Missense Mutation COAD
303 C → C 0.001887 SNP Silent UCEC
318 R → C 0.002141 SNP Missense Mutation SKCM