Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| M0QXM4 | SLC1A5 | Amino acid transporter | Homo sapiens (Human) | 365 aa |
Protein Details: M0QXM4 (SLC1A5)
Protein Information
| Accession | M0QXM4 |
|---|---|
| Protein Names | Amino acid transporter |
| Gene Symbol | SLC1A5 |
| Organism | Homo sapiens (Human) |
| Length | 365 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 29575903 31251020 32651440 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.818
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.818
36/46 (78.3%)
4
PC3 cells
Specificity: 0.091
4/4 (100.0%)
3
Jurkat T cells
Specificity: 0.068
3/25 (12.0%)
1
HeLa cells
Specificity: 0.023
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MVSNNPLCVC11LCRNIFPSNL21VSAAFRSYST31TYEERNITGT41RVKVPVGQEV
51-10051EGMNILGLVV61FAIVFGVALR71KLGPEGELLI81RFFNSFNEAT91MVLVSWIMWY
101-150101APVGIMFLVA111GKIVEMEDVG121LLFARLGKYI131LCCLLGHAIH141GLLVLPLIYF
151-200151LFTRKNPYRF161LWGIVTPLAT171AFGTSSSSAT181LPLMMKCVEE191NNGVAKHISR
201-250201FILPIGATVN211MDGAALFQCV221AAVFIAQLSQ231QSLDFVKIIT241ILVTATASSV
251-300251GAAGIPAGGV261LTLAIILEAV271NLPVDHISLI281LAVDWLVDRS291CTVLNVEGDA
301-350301LGAGLLQNYV311DRTESRSTEP321ELIQVKSELP331LDPLPVPTEE341GNPLLKHYRG
351-365351PAGDATVASE361KESVM
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 8 | Prediction (High) | - | - |
| 10 | Prediction (Medium) | - | - |
| 12 | Prediction (Medium) | - | - |
| 132 | Prediction (Medium) | - | - |
| 133 | Prediction (Medium) | - | - |
| 291 | CYSMODDB SWISSPALM DBPTM Prediction (Low) | Sodium:dicarboxylate symporter family | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 202 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 305 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 330 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 395 | C → C | 0.004577 | SNP | Silent | STAD |
| 405 | S → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 467 | C → _V469delinsF | 0.002976 | DEL | In Frame Del | KIRC |