Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| M0QY43 | MYH14 | Myosin heavy chain 14 | Homo sapiens (Human) | 1002 aa |
Protein Details: M0QY43 (MYH14)
Protein Information
| Accession | M0QY43 |
|---|---|
| Protein Names | Myosin heavy chain 14 |
| Gene Symbol | MYH14 |
| Organism | Homo sapiens (Human) |
| Length | 1002 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 31251020 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.854
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.854
35/46 (76.1%)
3
Cerebral cortex
Specificity: 0.073
3/4 (75.0%)
2
Jurkat T cells
Specificity: 0.049
2/25 (8.0%)
1
PC3 cells
Specificity: 0.024
1/4 (25.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAVTMSVPG11RKAPPRPGPV21PEAAQPFLFT31PRGPSAGGGP41GSGTSPQVEW
51-10051TARRLVWVPS61ELHGFEAAAL71RDEGEEEAEV81ELAESGRRLR91LPRDQIQRMN
101-150101PPKFSKAEDM111AELTCLNEAS121VLHNLRERYY131SGLIYTYSGL141FCVVINPYKQ
151-200151LPIYTEAIVE161MYRGKKRHEV171PPHVYAVTEG181AYRSMLQDRE191DQSILCTGES
201-250201GAGKTENTKK211VIQYLAHVAS221SPKGRKEPGV231PASVSTVSYG241ELERQLLQAN
251-300251PILEAFGNAK261TVKNDNSSRF271GKFIRINFDV281AGYIVGANIE291TYLLEKSRAI
301-350301RQAKDECSFH311IFYQLLGGAG321EQLKADLLLE331PCSHYRFLTN341GPSSSPGQER
351-400351ELFQETLESL361RVLGFSHEEI371ISMLRMVSAV381LQFGNIALKR391ERNTDQATMP
401-450401DNTAAQKLCR411LLGLGVTDFS421RALLTPRIKV431GRDYVQKAQT441KEQADFALEA
451-500451LAKATYERLF461RWLVLRLNRA471LDRSPRQGAS481FLGILDIAGF491EIFQLNSFEQ
501-550501LCINYTNEKL511QQLFNHTMFV521LEQEEYQREG531IPWTFLDFGL541DLQPCIDLIE
551-600551RPANPPGLLA561LLDEECWFPK571ATDKSFVEKV581AQEQGGHPKF591QRPRHLRDQA
601-650601DFSVLHYAGK611VDYKANEWLM621KNMDPLNDNV631AALLHQSTDR641LTAEIWKDVE
651-700651GIVGLEQVSS661LGDGPPGGRP671RRGMFRTVGQ681LYKESLSRLM691ATLSNTNPSF
701-750701VRCIVPNHEK711RAGKLEPRLV721LDQLRCNGVL731EGIRICRQGF741PNRILFQEFR
751-800751QRYEILTPNA761IPKGFMDGKQ771ACEKMIQALE781LDPNLYRVGQ791SKIFFRAGVL
801-850801AQLEEERDLK811VTDIIVSFQA821AARGYLARRA831FQKRQQQQSA841LRVMQRNCAA
851-900851YLKLRHWQWW861RLFTKVKPLL871QVTRQDEVLQ881ARAQELQKVQ891ELQQQSAREV
901-950901GELQGRVAQL911EEERARLAEQ921LRAEAELCAE931AEETRGRLAA941RKQELELVVS
951-1000951ELEARVGEEE961ECSRQMQTEK971KRLQQHIQEL981EAHLEAEEGA991RQKLQLEKVT
1001-10021001TE
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 115 | Prediction (Low) | - | - |
| 196 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Myosin head (motor domain) | - |
| 332 | Prediction (Medium) | - | - |
| 409 | Prediction (Medium) | - | - |
| 502 | Prediction (Medium) | - | - |
| 566 | Prediction (Medium) | - | - |
| 726 | Prediction (Low) | - | - |
| 736 | Prediction (Medium) | - | - |
| 772 | Prediction (Medium) | - | - |
| 848 | Prediction (High) | - | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 28 | L → Cfs*72 | 0.002976 | DEL | Frame Shift Del | KIRC |
| 54 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 54 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 154 | Y → C | 0.001969 | SNP | Missense Mutation | LGG |
| 167 | R → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 196 | C → C | 0.001887 | SNP | Splice Region | UCEC |
| 267 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 450 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 458 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 520 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 559 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 717 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 820 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 826 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 933 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 956 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 1024 | R → C | 0.004283 | SNP | Missense Mutation | SKCM |
| 1059 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 1237 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1267 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 1273 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1412 | R → C | 0.001969 | SNP | Missense Mutation | LGG |
| 1581 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1581 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 1629 | R → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 1665 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 1665 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 1665 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 1749 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 1754 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 1775 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 1794 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 1794 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 1826 | R → C | 0.002294 | SNP | Missense Mutation | OV |
| 1854 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1936 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1947 | R → C | 0.002288 | SNP | Missense Mutation | STAD |